Development of a Novel Class of Pyridazinone Derivatives as Selective MAO-B Inhibitors
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DOI: 10.3390/molecules27123801
Abstract: Sixteen compounds (TR1–TR16) were synthesized and evaluated for their inhibitory activities against monoamine oxidase A and B (MAOs). Most of the derivatives showed potent and highly selective MAO-B inhibition. Compound TR16 was the most potent… read more here.
Keywords: mao inhibitors; mao; tr2 tr16; selective mao ... See more keywords