Articles with "tr46 y121f" as a keyword



Itraconazole, Voriconazole, and Posaconazole CLSI MIC Distributions for Wild-Type and Azole-Resistant Aspergillus fumigatus Isolates

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Published in 2018 at "Journal of Fungi"

DOI: 10.3390/jof4030103

Abstract: Azole resistance in Aspergillus fumigatus is most frequently conferred by mutations in the cyp51A gene encoding 14α-sterol demethylases. TR34/L98H and TR46/Y121F/T289A are the two most common mutations associated with environmental resistance selection. We studied the… read more here.

Keywords: fumigatus isolates; aspergillus fumigatus; tr34 l98h; tr46 y121f ... See more keywords