Articles with "trabectedin lurbinectedin" as a keyword



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Effects of the Anti-Tumor Agents Trabectedin and Lurbinectedin on Immune Cells of the Tumor Microenvironment

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.851790

Abstract: Immune cells in the tumor micro-environment (TME) establish a complex relationship with cancer cells and may strongly influence disease progression and response to therapy. It is well established that myeloid cells infiltrating tumor tissues favor… read more here.

Keywords: oncology; anti tumor; trabectedin lurbinectedin; cells tumor ... See more keywords
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Specific Effects of Trabectedin and Lurbinectedin on Human Macrophage Function and Fate—Novel Insights

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Published in 2020 at "Cancers"

DOI: 10.3390/cancers12103060

Abstract: Simple Summary Trabectedin and lurbinectedin are two potent onco-therapeutic drugs for the treatment of advanced soft tissue sarcomas. Here we show that, in addition to cancer cells, these molecules exert important effects on macrophages and… read more here.

Keywords: viability; lurbinectedin human; trabectedin lurbinectedin; function ... See more keywords