Traceless Staudinger Ligation To Introduce Chemical Diversity on β-Lactamase Inhibitors of Second Generation.
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DOI: 10.1021/acs.orglett.1c02741
Abstract: We explored the traceless Staudinger ligation for the functionalization of the C2 position of second generation β-lactamase inhibitors based on a diazabicyclooctane (DBO) scaffold. Our strategy is based on the synthesis of phosphine phenol esters… read more here.
Keywords: staudinger ligation; traceless staudinger; second generation; lactamase inhibitors ... See more keywords