Development of the First Potential Nonpeptidic Positron Emission Tomography Tracer for the Imaging of CCR2 Receptors
Sign Up to like & getrecommendations! Published in 2020 at "Chemmedchem"
DOI: 10.1002/cmdc.202000728
Abstract: Herein we report the design and synthesis of a series of highly selective CCR2 antagonists as 18F‐labeled PET tracers. The derivatives were evaluated extensively for their off‐target profile at 48 different targets. The most potent… read more here.
Keywords: potential nonpeptidic; tracer imaging; ccr2 receptors; imaging ccr2 ... See more keywords
Impact of deep learning denoising on kinetic modelling for low-dose dynamic PET: application to single- and dual-tracer imaging protocols
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DOI: 10.1007/s00259-025-07182-6
Abstract: Long-axial field-of-view PET scanners capture multi-organ tracer distribution with high sensitivity, enabling lower dose dynamic protocols and dual-tracer imaging for comprehensive disease characterization. However, reducing dose may compromise data quality and time-activity curve (TAC) fitting,… read more here.
Keywords: tracer; tracer imaging; dual tracer; 18f fdg ... See more keywords
Feasibility of simultaneous 99mTc-tetrofosmin and 123I-BMIPP dual-tracer imaging with cadmium-zinc-telluride detectors in patients undergoing primary coronary intervention for acute myocardial infarction
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DOI: 10.1007/s12350-018-01585-9
Abstract: Background Simultaneous dual-tracer imaging using isotopes with close photo-peaks may benefit from improved properties of cadmium-zinc-telluride (CZT)-based scanners. Methods Thirty patients having undergone primary percutaneous coronary intervention for acute myocardial infarction underwent single-( 99m Tc-tetrofosmin… read more here.
Keywords: tracer imaging; infarction; tracer; bmipp dual ... See more keywords