Proposing a validation scheme for 13C metabolite tracer studies in high-resolution mass spectrometry
Sign Up to like & getrecommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-019-01773-7
Abstract: Abstract13C metabolite tracer and metabolic flux analyses require upfront experimental planning and validation tools. Here, we present a validation scheme including a comparison of different LC methods that allow for customization of analytical strategies for… read more here.
Keywords: high resolution; tracer studies; metabolite tracer; validation ... See more keywords
Unraveling metabolism during kidney perfusion using tracer studies, a systematic review.
Sign Up to like & getrecommendations! Published in 2022 at "Artificial organs"
DOI: 10.1111/aor.14355
Abstract: BACKGROUND Understanding kidney metabolism during perfusion is vital to further develop the technology as a preservation, viability assessment, and resuscitation platform. We reviewed the evidence on the use of labeled metabolites (tracers) to understand "on-pump"… read more here.
Keywords: metabolism; normothermic perfusion; kidney perfusion; kidney ... See more keywords