KCa3.1 differentially regulates trachea and bronchi epithelial gene expression in a chronic-asthma mouse model.
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DOI: 10.1152/physiolgenomics.00134.2021
Abstract: Ion channels are potentially exploitable as pharmacological targets to treat asthma. This study evaluated the role of KCa3.1 channels, encoded by Kcnn4, in regulating the gene expression of mouse airway epithelium and the development of… read more here.
Keywords: asthma; trachea bronchi; expression; gene expression ... See more keywords
The absence of SOX2 in the anterior foregut alters the esophagus into trachea and bronchi in both epithelial and mesenchymal components
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DOI: 10.1242/bio.048728
Abstract: ABSTRACT In the anterior foregut (AFG) of mouse embryos, the transcription factor SOX2 is expressed in the epithelia of the esophagus and proximal branches of respiratory organs comprising the trachea and bronchi, whereas NKX2.1 is… read more here.
Keywords: anterior foregut; absence sox2; epithelial mesenchymal; trachea bronchi ... See more keywords