Sublingual Boosting with a Novel Mucoadhesive Thermogelling Hydrogel Following Parenteral CAF01 Priming as a Strategy Against Chlamydia trachomatis
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102508
Abstract: Chlamydia trachomatis is the most prevalent sexually transmitted disease of bacterial origin. The high number of asymptomatic cases makes it difficult to stop the transmission, requiring vaccine development. Herein, a strategy is proposed to obtain… read more here.
Keywords: trachomatis; chlamydia; chlamydia trachomatis; sublingual boosting ... See more keywords
Whole-Genome Enrichment Using RNA Probes and Sequencing of Chlamydia trachomatis Directly from Clinical Samples.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7037-7_1
Abstract: Whole-genome sequencing is a powerful, high-resolution tool that can be used to generate accurate data on bacterial population structure, phylogeography, and mutations associated with antimicrobial resistance. The ability to sequence pathogen genomes directly from clinical… read more here.
Keywords: directly clinical; whole genome; chlamydia trachomatis; trachomatis ... See more keywords
Effects of iota-carrageenan on ocular Chlamydia trachomatis infection in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Phycology"
DOI: 10.1007/s10811-018-1435-0
Abstract: Ocular chlamydial infections with the ocular serovars A, B, Ba, and C of Chlamydia trachomatis represent the world’s leading cause of infectious blindness. Carrageenans are naturally occurring, sulfated polysaccharides generally considered safe for food and… read more here.
Keywords: vivo; iota carrageenan; infection; pathology ... See more keywords
Chlamydia trachomatis Infections in a Tertiary Care Portuguese Hospital: An 11-Year Retrospective Study.
Sign Up to like & getrecommendations! Published in 2021 at "Actas dermo-sifiliograficas"
DOI: 10.1016/j.adengl.2021.03.001
Abstract: BACKGROUND Chlamydia trachomatis infections remain a burden worldwide. The goals of this study were to determine the number of C. trachomatis infections per year, characterize the demographic traits of the infected population and identify the… read more here.
Keywords: trachomatis infections; infection; chlamydia trachomatis; year ... See more keywords
A novel protease inhibitor causes inclusion vacuole reduction and disrupts the intracellular growth of Chlamydia trachomatis.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.05.184
Abstract: Chlamydia (C.) trachomatis, characterized by a unique biphasic life cycle, is an obligate intracellular bacterial pathogen which is responsible for the highest number of sexually transmitted bacterial infections globally. However, its pathogenic mechanisms have not… read more here.
Keywords: inhibitor; protease; developmental cycle; chlamydia trachomatis ... See more keywords
Pooling of urine samples for molecular detection of Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium as a screening strategy among young adults in Catalonia.
Sign Up to like & getrecommendations! Published in 2019 at "Enfermedades infecciosas y microbiologia clinica"
DOI: 10.1016/j.eimc.2019.05.003
Abstract: INTRODUCTION Bacterial sexually transmitted infections (STIs) have an important impact on reproductive health, highlighting the increase in Chlamydia trachomatis infection rates among young people. To reduce the costs of STI detection, the pooling strategy is… read more here.
Keywords: among young; prevalence; strategy; trachomatis ... See more keywords
YAP1 induces marrow derived suppressor cell recruitment in Chlamydia trachomatis infection.
Sign Up to like & getrecommendations! Published in 2021 at "Immunology letters"
DOI: 10.1016/j.imlet.2021.12.003
Abstract: Chlamydia trachomatis (C. trachomatis) is the most commonly diagnosed bacterial sexually transmitted infection (STI) worldwide. Marrow derived suppressor cells (MDSCs) are a heterogeneous population of immature monocytes and granulocytes, which are effective inhibitors for T… read more here.
Keywords: marrow derived; chlamydia trachomatis; infection; trachomatis ... See more keywords
A FACS-Based Genome-wide CRISPR Screen Reveals a Requirement for COPI in Chlamydia trachomatis Invasion
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DOI: 10.1016/j.isci.2018.12.011
Abstract: The invasion of Chlamydia trachomatis, an obligate intracellular bacterium, into epithelial cells is driven by a complex interplay of host and bacterial factors. To comprehensively define the host genes required for pathogen invasion, we undertook… read more here.
Keywords: invasion; chlamydia trachomatis; facs based; trachomatis ... See more keywords
Intrauterine inoculation of minipigs with Chlamydia trachomatis during diestrus establishes a longer lasting infection compared to vaginal inoculation during estrus.
Sign Up to like & getrecommendations! Published in 2017 at "Microbes and infection"
DOI: 10.1016/j.micinf.2017.01.008
Abstract: Advanced animal models, such as minipigs, are needed for the development of a globally requested human Chlamydia vaccine. Previous studies have shown that vaginal inoculation of sexually mature Göttingen minipigs with Chlamydia trachomatis resulted in… read more here.
Keywords: inoculation; diestrus; infection; intrauterine inoculation ... See more keywords
Immunobiology of monocytes and macrophages during Chlamydia trachomatis infection.
Sign Up to like & getrecommendations! Published in 2019 at "Microbes and infection"
DOI: 10.1016/j.micinf.2018.10.007
Abstract: Infections caused by the intracellular bacterium Chlamydia trachomatis are a global health burden affecting more than 100 million people annually causing damaging long-lasting infections. In this review, we will present and discuss important aspects of… read more here.
Keywords: monocytes macrophages; immunobiology monocytes; chlamydia trachomatis; infection immunobiology ... See more keywords
Chlamydia trachomatis: Cell biology, immunology and vaccination.
Sign Up to like & getrecommendations! Published in 2021 at "Vaccine"
DOI: 10.1016/j.vaccine.2021.03.043
Abstract: Chlamydia trachomatis is the causative agent of a highly prevalent sexually transmitted bacterial disease and is associated with a number of severe disease complications. Current therapy options are successful at treating disease, but patients are… read more here.
Keywords: vaccine; disease; biology; chlamydia ... See more keywords