Chlamydia trachomatis glycogen synthase promotes MAPK-mediated proinflammatory cytokine production via TLR2/TLR4 in THP-1 cells.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119181
Abstract: AIMS To investigate the roles and mechanisms of C. trachomatis glycogen synthase (GlgA) in regulating the inflammatory response in THP-1 cells. MAIN METHODS In this work, after THP-1 cells were stimulated with GlgA, transcript and… read more here.
Keywords: glycogen synthase; trachomatis glycogen; tlr2 tlr4; thp cells ... See more keywords
Identification of HeLa cell proteins that interact with Chlamydia trachomatis glycogen synthase using yeast two-hybrid assays
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2020.10947
Abstract: Chlamydia trachomatis (C. trachomatis) is the leading cause of bacterial sexually transmitted diseases and infectious diseases that cause blindness. The pathophysiology of chlamydial infections is poorly understood, but secreted proteins have emerged as key virulence… read more here.
Keywords: glycogen synthase; using yeast; chlamydia trachomatis; trachomatis glycogen ... See more keywords