Split-tracrRNA as an efficient tracrRNA system with an improved potential of scalability.
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DOI: 10.1039/d2bm01901a
Abstract: Due to the relatively long sequence, tracrRNAs are chemically less synthesizable than crRNAs, leading to limited scalability of RNA guides for CRISPR-Cas9 systems. To develop shortened versions of RNA guides with improved cost-effectiveness, we have… read more here.
Keywords: split; tracrrna system; scalability; tracrrna ... See more keywords