Traction Force Microscopy in 3‐Dimensional Extracellular Matrix Networks
Sign Up to like & getrecommendations! Published in 2017 at "Current Protocols in Cell Biology"
DOI: 10.1002/cpcb.24
Abstract: Cell migration through a three‐dimensional (3‐D) matrix depends strongly on the ability of cells to generate traction forces. To overcome the steric hindrance of the matrix, cells need to generate sufficiently high traction forces but… read more here.
Keywords: microscopy; matrix; force; traction ... See more keywords
Regulation of SMC traction forces in human aortic thoracic aneurysms
Sign Up to like & getrecommendations! Published in 2021 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-020-01412-6
Abstract: Smooth muscle cells (SMCs) usually express a contractile phenotype in the healthy aorta. However, aortic SMCs have the ability to undergo profound changes in phenotype in response to changes in their extracellular environment, as occurs… read more here.
Keywords: smcs; smc traction; regulation smc; traction ... See more keywords
Phagocytosis: Mechanosensing, Traction Forces, and a Molecular Clutch
Sign Up to like & getrecommendations! Published in 2020 at "Current Biology"
DOI: 10.1016/j.cub.2019.11.047
Abstract: The forces driving membrane protrusion during phagocytosis are poorly understood. A recent study describes how integrins in the phagocyte membrane provide a molecular clutch to enable the exertion of force by actin polymerizing at the… read more here.
Keywords: molecular clutch; phagocytosis; mechanosensing traction; phagocytosis mechanosensing ... See more keywords
Coordination between Intra- and Extracellular Forces Regulates Focal Adhesion Dynamics.
Sign Up to like & getrecommendations! Published in 2017 at "Nano letters"
DOI: 10.1021/acs.nanolett.6b04364
Abstract: Focal adhesions (FAs) are important mediators of cell-substrate interactions. One of their key functions is the transmission of forces between the intracellular acto-myosin network and the substrate. However, the relationships between cell traction forces, FA… read more here.
Keywords: tension; coordination intra; intra extracellular; traction ... See more keywords
DNA Tension Probes Show that Cardiomyocyte Maturation Is Sensitive to the Piconewton Traction Forces Transmitted by Integrins.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.1c04303
Abstract: Cardiac muscle cells (CMCs) are the unit cells that comprise the heart. CMCs go through different stages of differentiation and maturation pathways to fully mature into beating cells. These cells can sense and respond to… read more here.
Keywords: cmcs; maturation; piconewton; traction forces ... See more keywords
Stress-induced plasticity of dynamic collagen networks
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-01011-7
Abstract: The structure and mechanics of tissues is constantly perturbed by endogenous forces originated from cells, and at the same time regulate many important cellular functions such as migration, differentiation, and growth. Here we show that… read more here.
Keywords: collagen; cellular traction; stress induced; traction forces ... See more keywords
Cellular traction forces: a useful parameter in cancer research.
Sign Up to like & getrecommendations! Published in 2017 at "Nanoscale"
DOI: 10.1039/c7nr06284b
Abstract: The search for new cancer biomarkers is essential for fundamental research, diagnostics, as well as for patient treatment and monitoring. Whereas most cancer biomarkers are biomolecules, an increasing number of studies show that mechanical cues… read more here.
Keywords: research; cellular traction; traction forces; cancer ... See more keywords
Quantifying stiffness and forces of tumor colonies and embryos using a magnetic microrobot
Sign Up to like & getrecommendations! Published in 2023 at "Science Robotics"
DOI: 10.1126/scirobotics.adc9800
Abstract: Stiffness and forces are two fundamental quantities essential to living cells and tissues. However, it has been a challenge to quantify both 3D traction forces and stiffness (or modulus) using the same probe in vivo.… read more here.
Keywords: traction forces; traction; microrobot; magnetic microrobot ... See more keywords
Increased Cell Traction-Induced Prestress in Dynamically Cultured Microtissues
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2019.00041
Abstract: Prestress is a phenomenon present in many cardiovascular tissues and has profound implications on their in vivo functionality. For instance, the in vivo mechanical properties are altered by the presence of prestress, and prestress also… read more here.
Keywords: traction forces; prestress; increased cell; tissue ... See more keywords