Direct formation of amide/peptide bonds from carboxylic acids: no traditional coupling reagents, 1-pot, and green
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DOI: 10.1039/d3sc00198a
Abstract: Technology for generating especially important amide and peptide bonds from carboxylic acids and amines that avoids traditional coupling reagents is described. The 1-pot processes developed rely on thioester formation, neat, using a simple dithiocarbamate, and… read more here.
Keywords: amide peptide; coupling reagents; peptide bonds; bonds carboxylic ... See more keywords