Cardiovascular Disease Risk Assessment Using Traditional Risk Factors and Polygenic Risk Scores in the Million Veteran Program.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2023.0857
Abstract: Importance Primary prevention of atherosclerotic cardiovascular disease (ASCVD) relies on risk stratification. Genome-wide polygenic risk scores (PRSs) are proposed to improve ASCVD risk estimation. Objective To determine whether genome-wide PRSs for coronary artery disease (CAD)… read more here.
Keywords: traditional risk; disease; risk factors; risk ... See more keywords
Traditional and Non-traditional Risk Factors for Osteoporosis in CKD.
Sign Up to like & getrecommendations! Published in 2021 at "Calcified tissue international"
DOI: 10.1007/s00223-020-00786-0
Abstract: Osteoporosis is a state of bone fragility with reduced skeletal resistance to trauma, and consequently increased risk of fracture. A wide range of conditions, including traditional risk factors, lifestyle choices, diseases and their treatments may… read more here.
Keywords: bone fragility; risk; risk factors; traditional risk ... See more keywords
Incremental value of epicardial fat volume to coronary artery calcium score and traditional risk factors for predicting myocardial ischemia in patients with suspected coronary artery disease
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Nuclear Cardiology"
DOI: 10.1007/s12350-021-02538-5
Abstract: Epicardial fat volume (EFV) has been reported to be associated with coronary artery disease (CAD). CAD is the leading cause of myocardial ischemia and myocardial ischemia is closely related to major adverse cardiovascular events. We… read more here.
Keywords: traditional risk; myocardial ischemia; risk factors; coronary artery ... See more keywords
Lipoprotein(a) screening in patients with controlled traditional risk factors undergoing percutaneous coronary intervention.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of clinical lipidology"
DOI: 10.1016/j.jacl.2017.07.005
Abstract: BACKGROUND Lipoprotein(a) [Lp(a)] is an inherited atherogenic lipoprotein and an independent risk factor for atherosclerotic cardiovascular disease; however, its clinical role remains limited. OBJECTIVE We hypothesized that Lp(a) screening in high cardiovascular risk patients could… read more here.
Keywords: risk; traditional risk; risk factors; cardiovascular risk ... See more keywords
MACHINE LEARNING VERSUS TRADITIONAL RISK STRATIFICATION METHODS IN ACUTE CORONARY SYNDROME: A POOLED RANDOMIZED CLINICAL TRIAL ANALYSIS
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(19)30866-6
Abstract: Traditional prediction models allow population based inferences. Machine learning explores datasets to develop algorithms that do not assume linear relationships between variables and outcomes and that account for higher order interactions to make individualized outcome… read more here.
Keywords: traditional risk; machine; learning versus; versus traditional ... See more keywords
CHLD score, a new score based on traditional risk factor evaluation and long-term cardiovascular outcomes in patients with systemic sclerosis
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-99215-x
Abstract: The aim of the study was to assess the predictors of major adverse cardiovascular events (MACE) in patients with systemic sclerosis (SSc) without pulmonary arterial hypertension. The study comprised 68 patients with SSc who were… read more here.
Keywords: risk; traditional risk; chld score; systemic sclerosis ... See more keywords
Combining serum metabolomic profiles with traditional risk factors improves 10-year cardiovascular risk prediction in people with type 2 diabetes.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of preventive cardiology"
DOI: 10.1093/eurjpc/zwad160
Abstract: AIMS To identify a group of metabolites associated with incident CVD in people with type 2 diabetes and assess its predictive performance over-and-above a current CVD risk score (QRISK3). METHODS A panel of 228 serum… read more here.
Keywords: traditional risk; people type; risk factors; risk ... See more keywords
Chronic kidney disease progression in kidney transplant recipients: A focus on traditional risk factors
Sign Up to like & getrecommendations! Published in 2019 at "Nephrology"
DOI: 10.1111/nep.13483
Abstract: Kidney transplant recipients are a subset of patients with chronic kidney disease (CKD) that remain at high risk for progression to dialysis and mortality. Recent advances in immunosuppression have only partially improved long‐term graft and… read more here.
Keywords: risk; traditional risk; kidney transplant; risk factors ... See more keywords
Predictive Utility of a Validated Polygenic Risk Score for Long-Term Risk of Coronary Heart Disease in Young and Middle-Aged Adults
Sign Up to like & getrecommendations! Published in 2022 at "Circulation"
DOI: 10.1161/circulationaha.121.058426
Abstract: Background: Understanding the predictive utility of previously derived polygenic risk scores (PRSs) for long-term risk of coronary heart disease (CHD) and its additive value beyond traditional risk factors can inform prevention strategies. Methods: Data from… read more here.
Keywords: traditional risk; age; risk factor; risk ... See more keywords
[Genetic Polymorphisms Associated with the Onset of Arterial Hypertension in a Portuguese Population].
Sign Up to like & getrecommendations! Published in 2018 at "Acta medica portuguesa"
DOI: 10.20344/amp.9184
Abstract: INTRODUCTION Arterial hypertension is a complex, multifactorial disease, controlled by genetic and environmental factors. OBJECTIVE Evaluate the genetic susceptibility for developing arterial hypertension and its association with the traditional risk factors in the outbreak of… read more here.
Keywords: risk; traditional risk; genetic variants; risk factors ... See more keywords
Negative Risk Markers for Cardiovascular Risk Evaluation in Chinese Adults
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.800671
Abstract: Background The atherosclerotic cardiovascular disease (ASCVD) risk predicted by traditional risk factors is used to guide preventive treatment. We aimed to investigate whether preferable levels of non-traditional emerging risk factors (i.e., negative risk markers) could… read more here.
Keywords: traditional risk; chinese adults; risk; risk markers ... See more keywords