The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1
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DOI: 10.1038/s41467-017-01665-3
Abstract: Ubiquitin chains linked through lysine63 (K63) play a critical role in inflammatory signalling. Following ligand engagement of immune receptors, the RING E3 ligase TRAF6 builds K63-linked chains together with the heterodimeric E2 enzyme Ubc13-Uev1A. Dimerisation… read more here.
Keywords: traf6; zinc finger; activity; ubiquitin chains ... See more keywords