Up-regulation of TRAF2 inhibits chondrocytes apoptosis in lumbar facet joint osteoarthritis.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.07.096
Abstract: Tumor necrosis factor receptor-associated factor 2 (TRAF2) has been demonstrated that it plays a significant role in cell death receptor signal transduction. The purpose of this study was to investigate the expression of TRAF2 and… read more here.
Keywords: regulation traf2; traf2; traf2 inhibits; chondrocytes apoptosis ... See more keywords
TSG‐6 inhibits hypertrophic scar fibroblast proliferation by regulating IRE1α/TRAF2/NF‐κB signalling
Sign Up to like & getrecommendations! Published in 2022 at "International Wound Journal"
DOI: 10.1111/iwj.13950
Abstract: TNF‐stimulated gene (TSG‐6) was reported to suppress hypertrophic scar (HS) formation in a rabbit ear model, and the overexpression of TSG‐6 in human HS fibroblasts (HSFs) was found to induce their apoptotic death. The molecular… read more here.
Keywords: traf2 signalling; hypertrophic scar; tsg; proliferation ... See more keywords
TRAF2 Knockdown in Nasopharyngeal Carcinoma Induced Cell Cycle Arrest and Enhanced the Sensitivity to Radiotherapy
Sign Up to like & getrecommendations! Published in 2020 at "BioMed Research International"
DOI: 10.1155/2020/1641340
Abstract: TRAF2 is a crucial adaptor protein involved in various signaling pathways. However, its biological functions in nasopharyngeal carcinoma (NPC) remain largely unknown. In the present study, we found that TRAF2 was overexpressed in nasopharyngeal carcinoma… read more here.
Keywords: traf2 knockdown; nasopharyngeal carcinoma; traf2; cell cycle ... See more keywords
MicroRNA-647 promotes the therapeutic effectiveness of argon–helium cryoablation and inhibits cell proliferation through targeting TRAF2 via the NF-κB signaling pathway in non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2018 at "OncoTargets and therapy"
DOI: 10.2147/ott.s159337
Abstract: Background MicroRNA-647 (miR-647) has been reported to repress cell tumorigenic phenotype, while the function of miR-647 in non-small cell lung cancer was obscure. Methods The effect of miR-647 and TRAF2 on A549 and H1299 cells… read more here.
Keywords: traf2; mir 647; non small; cell ... See more keywords
One for All, All for One: The Peculiar Dynamics of TNF-Receptor-Associated Factor (TRAF2) Subunits
Sign Up to like & getrecommendations! Published in 2022 at "Symmetry"
DOI: 10.3390/sym14040720
Abstract: TNF Receptor-Associated Factor 2 (TRAF2) is a homo-trimer belonging to the TNF-receptor-associated factor family (TRAFs). The TRAF2 oligomeric state is crucial for receptor binding, the interaction with other proteins (involved in the TNFR signaling), and… read more here.
Keywords: tnf receptor; traf2; receptor; receptor associated ... See more keywords
High glucose and bupivacaine-induced cytotoxicity is mediated by enhanced apoptosis and impaired autophagy via the PERK-ATF4-CHOP and IRE1-TRAF2 signaling pathways
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2019.10524
Abstract: Bupivacaine has previously been reported to induce neurotoxicity, which is further enhanced by high glucose levels. In the present study, the underlying molecular mechanisms via which bupivacaine induces cytotoxicity under high glucose conditions were investigated… read more here.
Keywords: apoptosis; traf2; glucose bupivacaine; high glucose ... See more keywords