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   Articles with "traf5" as a keyword



Downregulation of long noncoding RNA SNHG7 protects against inflammation and apoptosis in Parkinson's disease model by targeting the miR‐425‐5p/TRAF5/NF‐κB axis

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recommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.22867

Abstract: Accumulated evidence has manifested that long noncoding RNA (lncRNA) is involved in the progress of Parkinson's disease (PD). SNHG7, a novel lncRNA, has been found to be involved in tumorigenesis. However, SNHG7 expression and its… read more here.

Keywords: apoptosis; mir 425; rna; traf5 ... See more keywords

Two new IncRNAs regulate the key immune factor NOD1 and TRAF5 in chicken lymphocyte

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recommendations! Published in 2019 at "Journal of Integrative Agriculture"

DOI: 10.1016/s2095-3119(19)62722-x

Abstract: Abstract Reticuloendotheliosis virus (REV) causes the atrophy of immune organs and immuno-suppression in chickens, but the underlying molecular mechanism of the immune response after infection by REV is not well understood. Presently, the RNA-seq was… read more here.

Keywords: two new; traf5; new incrnas; factor ... See more keywords
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Silenced lncRNA DDX11-AS1 or up-regulated microRNA-34a-3p inhibits malignant phenotypes of hepatocellular carcinoma cells via suppression of TRAF5

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recommendations! Published in 2021 at "Cancer Cell International"

DOI: 10.1186/s12935-021-01847-6

Abstract: Background Studies have discussed long noncoding RNA DDX11-AS1 (DDX11-AS1)-mediated downstream mechanism in hepatocellular carcinoma (HCC). The goal of this study was to investigate the regulatory mechanism of DDX11-AS1-mediated microRNA-34a-3p (miR-34a-3p)/tumor necrosis factor receptor-associated factor 5… read more here.

Keywords: hcc; mir 34a; as1; traf5 ... See more keywords

Tumor necrosis factor receptor-associated factor 5 enhances perianal fistulizing Crohn’s disease through epithelial–mesenchymal transition

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recommendations! Published in 2024 at "CytoJournal"

DOI: 10.25259/cytojournal_148_2024

Abstract: Objective: Crohn’s disease (CD) is a chronic inflammatory condition of the bowel that remarkably impairs a patient’s quality of life and often has a poor prognosis. Perianal fistulizing CD (PFCD) is one of the most… read more here.

Keywords: pfcd; crohn disease; perianal fistulizing; factor ... See more keywords

Defective IgG Class Switching in the Spleen of TRAF5-Deficient Mice Reveals a Role for TRAF5 in CD40-Mediated B Cell Responses During Obesity-Associated Inflammation

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recommendations! Published in 2025 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms26199494

Abstract: Tumor necrosis factor receptor-associated factors (TRAFs) are a family of adaptor proteins that transmit signals from immunoregulatory receptors—such as TNF receptors, Toll-like receptors, and interleukin receptors—to coordinate immune and inflammatory responses. Among them, TRAF5 is… read more here.

Keywords: mice; cd40; obesity associated; inflammation ... See more keywords

TNF Receptor-Associated Factor 5 Limits IL-27 Receptor Signaling in CD4+ T Lymphocytes.

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recommendations! Published in 2022 at "Journal of immunology"

DOI: 10.4049/jimmunol.2001358

Abstract: TNF receptor-associated factor 5 (TRAF5) restrains early signaling activity of the IL-6 receptor in naive CD4+ T cells by interacting with the shared gp130 chain, although TRAF5 was initially discovered as a cytoplasmic adaptor protein… read more here.

Keywords: tnf receptor; cd4 cells; cd4; receptor signaling ... See more keywords

Interleukin 17A promotes glycolysis to activate human hepatic stellate cells by mediating the TRAF2/TRAF5/HuR/PFKFB3 axis

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recommendations! Published in 2024 at "Central-European Journal of Immunology"

DOI: 10.5114/ceji.2024.145013

Abstract: Introduction Biliary atresia (BA) is an obliterating fibrous inflammatory bile duct disease in infants. Interleukin 17A (IL-17A) is abnormally expressed in patients with BA; however, the mechanism of its expression is unclear. Material and methods… read more here.

Keywords: pfkfb3; expression; traf5; traf2 traf5 ... See more keywords