Impaired central tolerance induces changes in the gut microbiota that exacerbate autoimmune hepatitis.
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DOI: 10.1016/j.jaut.2022.102808
Abstract: Medullary thymic epithelial cells (mTECs) induce T cell tolerance in the thymus through the elimination of self-reactive thymocytes. Commensal bacteria are also critical for shaping T cell responses in the gut and distal organs. We… read more here.
Keywords: gut microbiota; traf6 tec; autoimmune hepatitis; aih development ... See more keywords