Participation of OCRL1, and APPL1, in the expression, proteolysis, phosphorylation and endosomal trafficking of megalin: Implications for Lowe Syndrome
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DOI: 10.3389/fcell.2022.911664
Abstract: Megalin/LRP2 is the primary multiligand receptor for the re-absorption of low molecular weight proteins in the proximal renal tubule. Its function is significantly dependent on its endosomal trafficking. Megalin recycling from endosomal compartments is altered… read more here.
Keywords: megalin; endosomal trafficking; lowe syndrome; trafficking megalin ... See more keywords