A simplified method for the efficient purification and refolding of recombinant human TRAIL
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Progress"
DOI: 10.1002/btpr.3007
Abstract: Tumor necrosis factor (TNF)‐related apoptosis‐inducing ligand (TRAIL) belongs to the TNF cytokine superfamily that specifically induces apoptosis in a broad spectrum of human cancer cell lines but not in most healthy cells. The antitumor potential… read more here.
Keywords: recombinant human; efficient purification; trail; human trail ... See more keywords
Involvement of Bid in the crosstalk between ferroptotic agent‐induced ER stress and TRAIL‐induced apoptosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30863
Abstract: Tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) induces death receptor‐mediated extrinsic apoptosis, specifically in cancer cells, and Bid (BH3‐interacting domain death agonist) plays an important role in TRAIL‐induced apoptosis. Ferroptosis is a newly defined form of… read more here.
Keywords: crosstalk ferroptotic; trail; bid; trail induced ... See more keywords
Proteome and phosphoproteome profiling of non‐small cell lung cancer cell line A549 treated with TRAIL
Sign Up to like & getrecommendations! Published in 2022 at "PROTEOMICS"
DOI: 10.1002/pmic.202200248
Abstract: Tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) is recognized for its promising therapeutic effects against cancer. However, mechanisms underlying the effect of TRAIL on protein expression, signal transduction, and apoptosis induction remain unclear. We surmised that… read more here.
Keywords: trail; cell; non small; small cell ... See more keywords
Nanoscale Organization of TRAIL Trimers using DNA Origami to Promote Clustering of Death Receptor and Cancer Cell Apoptosis.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202206160
Abstract: Through inducing death receptor (DR) clustering to activate downstream signaling, tumor necrosis factor related apoptosis inducing ligand (TRAIL) trimers trigger apoptosis of tumor cells. However, the poor agonistic activity of current TRAIL-based therapeutics limits their… read more here.
Keywords: trail; death receptor; dna; trail trimers ... See more keywords
Ethanol induces interferon expression in neurons via TRAIL: role of astrocyte-to-neuron signaling
Sign Up to like & getrecommendations! Published in 2019 at "Psychopharmacology"
DOI: 10.1007/s00213-018-5153-8
Abstract: RationaleAlcohol use disorder (AUD) involves dysregulation of innate immune signaling in brain. Toll-like receptor 3 (TLR3), an innate immune receptor that is upregulated in post-mortem human alcoholics, leads to induction of interferon (IFN) signaling. IFNs… read more here.
Keywords: role astrocyte; trail; astrocyte neuron; ifn ... See more keywords
Skid Trail Effects on Soil Methane and Carbon Dioxide Flux in a Selection-Managed Northern Hardwood Forest
Sign Up to like & getrecommendations! Published in 2021 at "Ecosystems"
DOI: 10.1007/s10021-020-00591-8
Abstract: Temperate forest soils are an important sink for methane (CH4); however, disturbance through forest management and the creation of skid trails may significantly decrease soil’s ability to uptake CH4 or in some cases cause CH4… read more here.
Keywords: skid trail; skid trails; selection managed; trail ... See more keywords
Encorafenib enhances TRAIL-induced apoptosis of colorectal cancer cells dependent on p53/PUMA signaling
Sign Up to like & getrecommendations! Published in 2020 at "Cytotechnology"
DOI: 10.1007/s10616-020-00442-3
Abstract: TRAIL has been demonstrated to play a critical role in the apoptosis of colorectal cancer (CRC) cells, but drug resistance markedly restricts its therapeutic effects. Objectives: This study aims to investigate whether encorafenib can enhance… read more here.
Keywords: trail; crc cells; trail induced; p53 puma ... See more keywords
Identification of the Trail Pheromone of the Carpenter Ant Camponotus modoc
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Chemical Ecology"
DOI: 10.1007/s10886-019-01114-z
Abstract: Trail pheromones deposited by ants lead nestmates to food sources. Based on previous evidence that the trail pheromone of the carpenter ant Camponotus modoc originates from the hindgut, our objective in this study was to… read more here.
Keywords: trail; camponotus; modoc; pheromone carpenter ... See more keywords
Cuticular Hydrocarbon Trails Released by Host Larvae Lose their Kairomonal Activity for Parasitoids by Solidification.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of chemical ecology"
DOI: 10.1007/s10886-021-01310-w
Abstract: Successful host search by parasitic wasps is often mediated by host-associated chemical cues. The ectoparasitoid Holepyris sylvanidis is known to follow chemical trails released by host larvae of the confused flour beetle, Tribolium confusum, for… read more here.
Keywords: kairomonal activity; hexane; trail; host ... See more keywords
Behavioral Response of Little Fire Ant, Wasmannia auropunctata (Hymenoptera: Formicidae), to Trail Chemicals Laid on Epiphytic Moss
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Insect Behavior"
DOI: 10.1007/s10905-019-09721-0
Abstract: The little fire ant (LFA), Wasmannia auropunctata (Hymenoptera: Formicidae), is native to the neotropics, but has become one of the world’s most widespread and destructive invasive ants. In Hawaii, LFA was first discovered in 1999… read more here.
Keywords: little fire; epiphytic moss; trail; lfa ... See more keywords
1H, 13C, 15N NMR resonance assignments and secondary structure determination of the extra-cellular domain from the human proapoptotic TRAIL-R2 death receptor 5 (DR5-ECD)
Sign Up to like & getrecommendations! Published in 2018 at "Biomolecular NMR Assignments"
DOI: 10.1007/s12104-018-9828-1
Abstract: Death receptors (DR) selectively drive cancer cells to apoptosis upon binding to the Tumor necrosis factor-a-Related Apoptosis-Inducing Ligand (TRAIL). Complex formation induces the oligomerization of the death receptors DR4 (TRAIL-R1) and DR5 (TRAIL-R2) and transduces… read more here.
Keywords: trail; death; dr5 ecd; death receptor ... See more keywords