A simplified method for the efficient purification and refolding of recombinant human TRAIL
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Progress"
DOI: 10.1002/btpr.3007
Abstract: Tumor necrosis factor (TNF)‐related apoptosis‐inducing ligand (TRAIL) belongs to the TNF cytokine superfamily that specifically induces apoptosis in a broad spectrum of human cancer cell lines but not in most healthy cells. The antitumor potential… read more here.
Keywords: recombinant human; efficient purification; trail; human trail ... See more keywords
Recreational trail traffic counts and trail proximity as a driver of ungulate landscape utilization
Sign Up to like & getrecommendations! Published in 2025 at "Ecosphere"
DOI: 10.1002/ecs2.70305
Abstract: With continual growth in recreational trail use, it is becoming increasingly complicated to balance demands for outdoor recreation opportunities with wildlife conservation. To better understand how mule deer (Odocoileus hemionus) and Rocky Mountain elk (Cervus… read more here.
Keywords: trail proximity; traffic counts; trail; recreation ... See more keywords
Involvement of Bid in the crosstalk between ferroptotic agent‐induced ER stress and TRAIL‐induced apoptosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30863
Abstract: Tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) induces death receptor‐mediated extrinsic apoptosis, specifically in cancer cells, and Bid (BH3‐interacting domain death agonist) plays an important role in TRAIL‐induced apoptosis. Ferroptosis is a newly defined form of… read more here.
Keywords: crosstalk ferroptotic; trail; bid; trail induced ... See more keywords
Proteome and phosphoproteome profiling of non‐small cell lung cancer cell line A549 treated with TRAIL
Sign Up to like & getrecommendations! Published in 2022 at "PROTEOMICS"
DOI: 10.1002/pmic.202200248
Abstract: Tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) is recognized for its promising therapeutic effects against cancer. However, mechanisms underlying the effect of TRAIL on protein expression, signal transduction, and apoptosis induction remain unclear. We surmised that… read more here.
Keywords: trail; cell; non small; small cell ... See more keywords
Nanoscale Organization of TRAIL Trimers using DNA Origami to Promote Clustering of Death Receptor and Cancer Cell Apoptosis.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202206160
Abstract: Through inducing death receptor (DR) clustering to activate downstream signaling, tumor necrosis factor related apoptosis inducing ligand (TRAIL) trimers trigger apoptosis of tumor cells. However, the poor agonistic activity of current TRAIL-based therapeutics limits their… read more here.
Keywords: trail; death receptor; dna; trail trimers ... See more keywords
Ethanol induces interferon expression in neurons via TRAIL: role of astrocyte-to-neuron signaling
Sign Up to like & getrecommendations! Published in 2019 at "Psychopharmacology"
DOI: 10.1007/s00213-018-5153-8
Abstract: RationaleAlcohol use disorder (AUD) involves dysregulation of innate immune signaling in brain. Toll-like receptor 3 (TLR3), an innate immune receptor that is upregulated in post-mortem human alcoholics, leads to induction of interferon (IFN) signaling. IFNs… read more here.
Keywords: role astrocyte; trail; astrocyte neuron; ifn ... See more keywords
Skid Trail Effects on Soil Methane and Carbon Dioxide Flux in a Selection-Managed Northern Hardwood Forest
Sign Up to like & getrecommendations! Published in 2021 at "Ecosystems"
DOI: 10.1007/s10021-020-00591-8
Abstract: Temperate forest soils are an important sink for methane (CH4); however, disturbance through forest management and the creation of skid trails may significantly decrease soil’s ability to uptake CH4 or in some cases cause CH4… read more here.
Keywords: skid trail; skid trails; selection managed; trail ... See more keywords
Encorafenib enhances TRAIL-induced apoptosis of colorectal cancer cells dependent on p53/PUMA signaling
Sign Up to like & getrecommendations! Published in 2020 at "Cytotechnology"
DOI: 10.1007/s10616-020-00442-3
Abstract: TRAIL has been demonstrated to play a critical role in the apoptosis of colorectal cancer (CRC) cells, but drug resistance markedly restricts its therapeutic effects. Objectives: This study aims to investigate whether encorafenib can enhance… read more here.
Keywords: trail; crc cells; trail induced; p53 puma ... See more keywords
Identification of the Trail Pheromone of the Carpenter Ant Camponotus modoc
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Chemical Ecology"
DOI: 10.1007/s10886-019-01114-z
Abstract: Trail pheromones deposited by ants lead nestmates to food sources. Based on previous evidence that the trail pheromone of the carpenter ant Camponotus modoc originates from the hindgut, our objective in this study was to… read more here.
Keywords: trail; camponotus; modoc; pheromone carpenter ... See more keywords
Cuticular Hydrocarbon Trails Released by Host Larvae Lose their Kairomonal Activity for Parasitoids by Solidification.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of chemical ecology"
DOI: 10.1007/s10886-021-01310-w
Abstract: Successful host search by parasitic wasps is often mediated by host-associated chemical cues. The ectoparasitoid Holepyris sylvanidis is known to follow chemical trails released by host larvae of the confused flour beetle, Tribolium confusum, for… read more here.
Keywords: kairomonal activity; hexane; trail; host ... See more keywords
Identification of Trail Following and Alarm Pheromones of Lasius Flavus Using Bioassay-Directed Fractionation
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Chemical Ecology"
DOI: 10.1007/s10886-025-01651-w
Abstract: The identity of trail following pheromones secreted by the ant Lasius flavus were investigated using bioassay-directed fractionation techniques. Extracts of whole bodies were fractionated by high performance liquid chromatography and fractions tested for trail following… read more here.
Keywords: directed fractionation; bioassay directed; trail following; lasius flavus ... See more keywords