LAUSR

TRAIL Induces Nuclear Translocation and Chromatin Localization of TRAIL Death Receptors

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1 Published in 2019 at "Cancers"

DOI: 10.3390/cancers11081167

Abstract: Binding of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to the plasma membrane TRAIL-R1/-R2 selectively kills tumor cells. This discovery led to evaluation of TRAIL-R1/-R2 as targets for anti-cancer therapy, yet the corresponding clinical trials were… read more here.

Keywords: trail induces; trail; chromatin; induces nuclear ... See more keywords