Multiple Interactions Between Cancer Cells and the Tumor Microenvironment Modulate TRAIL Signaling: Implications for TRAIL Receptor Targeted Therapy
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DOI: 10.3389/fimmu.2019.01530
Abstract: Tumor necrosis factor (TNF) related apoptosis-inducing ligand (TRAIL) signaling is far more complex than initially anticipated and can lead to either anti- or protumorigenic effects, hampering the successful clinical use of therapeutic TRAIL receptor agonists.… read more here.
Keywords: trail signaling; trail; trail receptor; tumor microenvironment ... See more keywords