Are trait‐associated genes clustered together in a gene network?
Sign Up to like & getrecommendations! Published in 2024 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22557
Abstract: Genome‐wide association studies (GWAS) have provided an abundance of information about the genetic variants and their loci that are associated to complex traits and diseases. However, due to linkage disequilibrium (LD) and noncoding regions of… read more here.
Keywords: trait associated; trait; associated genes; gene network ... See more keywords
cis-Acting Complex-Trait-Associated lincRNA Expression Correlates with Modulation of Chromosomal Architecture.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.02.009
Abstract: Intergenic long noncoding RNAs (lincRNAs) are the largest class of transcripts in the human genome. Although many have recently been linked to complex human traits, the underlying mechanisms for most of these transcripts remain undetermined. We… read more here.
Keywords: trait; trait associated; trait relevant; chromosomal architecture ... See more keywords
Genomewide association analyses of fitness traits in captive‐reared Chinook salmon: Applications in evaluating conservation strategies
Sign Up to like & getrecommendations! Published in 2018 at "Evolutionary Applications"
DOI: 10.1111/eva.12599
Abstract: A novel application of genomewide association analyses is to use trait‐associated loci to monitor the effects of conservation strategies on potentially adaptive genetic variation. Comparisons of fitness between captive‐ and wild‐origin individuals, for example, do… read more here.
Keywords: associated loci; trait associated; conservation; genomewide association ... See more keywords