CSGRqtl: A Comparative Quantitative Trait Locus Database for Saccharinae Grasses.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6658-5_15
Abstract: Conventional biparental quantitative trait locus (QTL) mapping has led to some successes in the identification of causal genes in many organisms. QTL likelihood intervals not only provide "prior information" for finer-resolution approaches such as GWAS… read more here.
Keywords: trait locus; csgrqtl comparative; quantitative trait; saccharinae ... See more keywords
Characterization of a major quantitative trait locus on the short arm of chromosome 4B for spike number per unit area in common wheat (Triticum aestivum L.)
Sign Up to like & getrecommendations! Published in 2020 at "Theoretical and Applied Genetics"
DOI: 10.1007/s00122-020-03595-z
Abstract: An InDel marker closely linked with a major and stable quantitative trait locus (QTL) on chromosome 4BS, QSnpa.cau-4B, controlling spike number per unit area will benefit wheat yield improvement. Spike number per unit area (SNPA)… read more here.
Keywords: trait; wheat; quantitative trait; trait locus ... See more keywords
Statistical power in genome-wide association studies and quantitative trait locus mapping
Sign Up to like & getrecommendations! Published in 2019 at "Heredity"
DOI: 10.1038/s41437-019-0205-3
Abstract: Power calculation prior to a genetic experiment can help investigators choose the optimal sample size to detect a quantitative trait locus (QTL). Without the guidance of power analysis, an experiment may be underpowered or overpowered.… read more here.
Keywords: power analysis; quantitative trait; power; association ... See more keywords
Quantitative trait locus (xQTL) approaches identify risk genes and drug targets from non-coding genome findings.
Sign Up to like & getrecommendations! Published in 2022 at "Human molecular genetics"
DOI: 10.1093/hmg/ddac208
Abstract: Advances and reduction of costs in various sequencing technologies allows for a closer look at variations present in the non-coding regions of the human genome. Correlating non-coding variants with large-scale multi-omics data holds the promise… read more here.
Keywords: trait locus; locus xqtl; quantitative trait; risk genes ... See more keywords
Effects of Coronary Artery Disease–Associated Variants on Vascular Smooth Muscle Cells
Sign Up to like & getrecommendations! Published in 2022 at "Circulation"
DOI: 10.1161/circulationaha.121.058389
Abstract: Background: Genome-wide association studies have identified many genetic loci that are robustly associated with coronary artery disease (CAD). However, the underlying biological mechanisms are still unknown for most of these loci, hindering the progress to… read more here.
Keywords: trait locus; quantitative trait; associated variants; cad ... See more keywords
Airway wall splice quantitative trait locus analysis reveals novel downstream mechanisms for known asthma single-nucleotide polymorphisms
Sign Up to like & getrecommendations! Published in 2023 at "ERJ Open Research"
DOI: 10.1183/23120541.00413-2022
Abstract: Genome-wide association studies (GWAS) [1] have identified single-nucleotide polymorphisms (SNPs) associated with the presence of asthma. It is notoriously difficult to link identified SNPs to downstream functional effects leading to increased asthma risk. A possible… read more here.
Keywords: trait locus; nucleotide polymorphisms; airway wall; quantitative trait ... See more keywords
Quantitative Trait Locus Mapping and Identification of Candidate Genes Controlling Bolting in Spinach (Spinacia oleracea L.)
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.850810
Abstract: Spinach is a typical light-sensitive plant. Long days can induce early bolting, thereby influencing the regional adaptation, quality, and vegetative yield of spinach. However, the genes and genetic mechanisms underlying this trait in spinach remain… read more here.
Keywords: bolting spinach; trait locus; locus; quantitative trait ... See more keywords