Discovering significant evolutionary trajectories in cancer phylogenies.
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DOI: 10.1093/bioinformatics/btac467
Abstract: MOTIVATION Tumors are the result of a somatic evolutionary process leading to substantial intra-tumor heterogeneity. Single-cell and multi-region sequencing enable the detailed characterization of the clonal architecture of tumors and have highlighted its extensive diversity… read more here.
Keywords: discovering significant; evolutionary trajectories; significant evolutionary; cancer phylogenies ... See more keywords