Reconstruction of complex single-cell trajectories using CellRouter
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-03214-y
Abstract: A better understanding of the cell-fate transitions that occur in complex cellular ecosystems in normal development and disease could inform cell engineering efforts and lead to improved therapies. However, a major challenge is to simultaneously… read more here.
Keywords: single cell; trajectories using; cellrouter; reconstruction complex ... See more keywords
Efficient generation of barrier crossing trajectories using approximate Brownian bridges.
Sign Up to like & getrecommendations! Published in 2024 at "Physical review. E"
DOI: 10.1103/physreve.110.024131
Abstract: We examine continuous random walks that are conditioned to reach one region before another. These conditioned processes are used to generate stochastic trajectories for barrier crossing events, which are generally rare and difficult to sample.… read more here.
Keywords: crossing trajectories; efficient generation; generation barrier; barrier ... See more keywords