Trametinib Induces Neurofibroma Shrinkage and Enables Surgery.
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DOI: 10.1055/s-0039-1691830
Abstract: Plexiform neurofibromas are congenital peripheral nerve sheath tumors characteristic of neurofibromatosis type 1 (NF1)-a frequent neurocutaneous disorder caused by mutations of the NF1 tumor suppressor gene. Since plexiform neurofibromas are a major cause of the… read more here.
Keywords: surgery; plexiform neurofibromas; induces neurofibroma; plexiform ... See more keywords