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   Articles with "tramp" as a keyword



The triterpenoid corosolic acid blocks transformation and epigenetically reactivates Nrf2 in TRAMP‐C1 prostate cells

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recommendations! Published in 2018 at "Molecular Carcinogenesis"

DOI: 10.1002/mc.22776

Abstract: Corosolic acid (CRA) is found in various plants and has been used as a health food supplement worldwide. Although it has been reported that CRA exhibits significant anticancer activity, the effect of this compound on… read more here.

Keywords: prostate; corosolic acid; prostate cells; tramp ... See more keywords

N-Terminus of Cid14 Activates RNA Unwinding by Mtr4 in the Schizosaccharomyces pombe TRAMP Complex.

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recommendations! Published in 2025 at "Biochemistry"

DOI: 10.1021/acs.biochem.5c00159

Abstract: The TRAMP (Trf4-Air2-Mtr4 polyadenylation) complex is a multiprotein assembly that targets RNA substrates for processing or degradation by the nuclear exosome. In Saccharomyces cerevisiae, the helicase activity of Mtr4 is enhanced by TRAMP assembly. Here… read more here.

Keywords: schizosaccharomyces pombe; helicase; mtr4 schizosaccharomyces; tramp ... See more keywords

Curcumin Derivative Epigenetically Reactivates Nrf2 Antioxidative Stress Signaling in Mouse Prostate Cancer TRAMP C1 Cells.

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recommendations! Published in 2018 at "Chemical research in toxicology"

DOI: 10.1021/acs.chemrestox.7b00248

Abstract: The carcinogenesis of prostate cancer (PCa) in TRAMP model is highly correlated with hypermethylation in the promoter region of Nrf2 and the accompanying reduced transcription of Nrf2 and its regulated detoxifying genes. We aimed to… read more here.

Keywords: prostate cancer; f10; tramp; f10 e10 ... See more keywords

Stage-Specific Effect of Inositol Hexaphosphate on Cancer Stem Cell Pool during Growth and Progression of Prostate Tumorigenesis in TRAMP Model

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recommendations! Published in 2022 at "Cancers"

DOI: 10.3390/cancers14174204

Abstract: Simple Summary The stage of a tumor during cancer intervention is the most crucial factor that determines the treatment regimen. Several bioactive natural compounds have shown potential to inhibit prostate cancer growth and progression; however,… read more here.

Keywords: tramp; progression; stage; growth progression ... See more keywords