The triterpenoid corosolic acid blocks transformation and epigenetically reactivates Nrf2 in TRAMP‐C1 prostate cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22776
Abstract: Corosolic acid (CRA) is found in various plants and has been used as a health food supplement worldwide. Although it has been reported that CRA exhibits significant anticancer activity, the effect of this compound on… read more here.
Keywords: prostate; corosolic acid; prostate cells; tramp ... See more keywords
Curcumin Derivative Epigenetically Reactivates Nrf2 Antioxidative Stress Signaling in Mouse Prostate Cancer TRAMP C1 Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.7b00248
Abstract: The carcinogenesis of prostate cancer (PCa) in TRAMP model is highly correlated with hypermethylation in the promoter region of Nrf2 and the accompanying reduced transcription of Nrf2 and its regulated detoxifying genes. We aimed to… read more here.
Keywords: prostate cancer; f10; tramp; f10 e10 ... See more keywords
Stage-Specific Effect of Inositol Hexaphosphate on Cancer Stem Cell Pool during Growth and Progression of Prostate Tumorigenesis in TRAMP Model
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14174204
Abstract: Simple Summary The stage of a tumor during cancer intervention is the most crucial factor that determines the treatment regimen. Several bioactive natural compounds have shown potential to inhibit prostate cancer growth and progression; however,… read more here.
Keywords: tramp; progression; stage; growth progression ... See more keywords