Association of Tranexamic Acid Administration With Mortality and Thromboembolic Events in Patients With Traumatic Injury
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DOI: 10.1001/jamanetworkopen.2022.0625
Abstract: Key Points Question Is the administration of tranexamic acid associated with mortality and thromboembolic events in patients with traumatic injury? Findings This systematic review and meta-analysis included 31 randomized clinical trials and observational studies with… read more here.
Keywords: traumatic injury; thromboembolic events; patients traumatic; mortality ... See more keywords
Effect of Tranexamic Acid Administration on Remote Cerebral Ischemic Lesions in Acute Spontaneous Intracerebral Hemorrhage: A Substudy of a Randomized Clinical Trial.
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DOI: 10.1001/jamaneurol.2022.0217
Abstract: Importance Hyperintense foci on diffusion-weighted imaging (DWI) that are spatially remote from the acute hematoma occur in 20% of people with acute spontaneous intracerebral hemorrhage (ICH). Tranexamic acid, a hemostatic agent that is under investigation… read more here.
Keywords: acute spontaneous; substudy; acid; tranexamic acid ... See more keywords
Evaluation of Military Use of Tranexamic Acid and Associated Thromboembolic Events
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DOI: 10.1001/jamasurg.2017.3821
Abstract: Importance Since publication of the CRASH-2 and MATTERs studies, the US military has included tranexamic acid (TXA) in clinical practice guidelines. While TXA was shown to decrease mortality in trauma patients requiring massive transfusion, improper… read more here.
Keywords: administration; txa administration; tranexamic acid; venous thromboembolism ... See more keywords
Use of tranexamic acid is not associated with complications following bipolar hemiarthroplasty for metastatic disease
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DOI: 10.1002/jso.26354
Abstract: Advances in the care of cancer patients have resulted in increased survival. The proximal femur is a common site for metastatic disease, often requiring surgical intervention. Tranexamic acid (TXA) has proven to be safe in… read more here.
Keywords: metastatic disease; tranexamic acid; use tranexamic; acid associated ... See more keywords
Tranexamic acid improves early postoperative mobilization in cancer patients undergoing endoprosthetic reconstruction
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DOI: 10.1002/jso.26830
Abstract: Tranexamic acid (TXA) has been shown to decrease perioperative blood loss, transfusions, and cost in patients undergoing resection of aggressive bone tumors and endoprosthetic reconstruction. This study explored the effect of TXA administration on postoperative… read more here.
Keywords: endoprosthetic reconstruction; postoperative mobilization; patients undergoing; tranexamic acid ... See more keywords
The antifibrinolytic and anti-inflammatory effects of a high initial-dose tranexamic acid in total knee arthroplasty: a randomized controlled trial
Sign Up to like & getrecommendations! Published in 2019 at "International Orthopaedics"
DOI: 10.1007/s00264-019-04469-w
Abstract: Purpose The aim of this study was to evaluate the effects of a high initial-dose (60 mg/kg) intravenous tranexamic acid (IV-TXA) on fibrinolysis and inflammation after total knee arthroplasty (TKA). Methods A total of 132 patients… read more here.
Keywords: initial dose; effects high; tranexamic acid; total knee ... See more keywords
Comment on the article “The antifibrinolytic and anti-inflammatory effects of a high initial-dose tranexamic acid in total knee arthroplasty: a randomized controlled trial”
Sign Up to like & getrecommendations! Published in 2020 at "International Orthopaedics"
DOI: 10.1007/s00264-020-04554-5
Abstract: To the Editor, I have read with great interest the article by Lei et al.—it has been an edifying experience to come across such a clinically relevant and important research where the authors have sought… read more here.
Keywords: initial dose; tranexamic acid; total knee; high initial ... See more keywords
Effectiveness of different doses and routes of administration of tranexamic acid for total hip replacement
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DOI: 10.1007/s00264-020-04585-y
Abstract: Purpose The aim of the study is to show the therapeutic efficacy, safety, and cost-benefit of using tranexamic acid (TXA), as well as the superiority of the route of administration and amount of dose in… read more here.
Keywords: administration; tranexamic acid; blood loss; blood ... See more keywords
Comparison of the Effect of Dexamethasone and Tranexamic Acid, Separately or in Combination on Post-Rhinoplasty Edema and Ecchymosis
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DOI: 10.1007/s00266-017-0969-x
Abstract: BackgroundDexamethasone and tranexamic acid are used to decrease post-rhinoplasty periorbital edema and ecchymosis. We compared the impact of each medication separately or in combination in this regard.MethodsA prospective, randomized triple-blinded study was undertaken on 60… read more here.
Keywords: periorbital edema; edema ecchymosis; tranexamic acid; group ... See more keywords
Commentary on: “Comparison of the Effect of Dexamethasone and Tranexamic Acid, Separately or in Combination on Post-rhinoplasty and Edema and Ecchymosis”
Sign Up to like & getrecommendations! Published in 2017 at "Aesthetic Plastic Surgery"
DOI: 10.1007/s00266-017-0997-6
Abstract: As the authors have underscored, there are many barriers to patients seeking rhinoplasty including financial, social, cultural, and recovery. Recovery from rhinoplasty is not insignificant. Patient testimonials on social media regarding pain, edema, and especially… read more here.
Keywords: dexamethasone tranexamic; comparison; tranexamic acid; edema ... See more keywords
Invited Commentary: A Decade Older Polytrauma Patients Do As Well Without As the Younger Ones with Tranexamic Acid
Sign Up to like & getrecommendations! Published in 2021 at "World Journal of Surgery"
DOI: 10.1007/s00268-021-06253-7
Abstract: CRASH-2, with over 20,000 subjects recruited in a trauma trial, found that the early administration of tranexamic acid (TXA) reduced all-cause mortality and the risk of death due to blood loss [1]. The uptake of… read more here.
Keywords: trial; tranexamic acid; trauma; older polytrauma ... See more keywords