Prolyl Isomerization-Mediated Conformational Changes Define ATR Subcellular Compartment-Specific Functions
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DOI: 10.3389/fcell.2022.826576
Abstract: ATR is a PI3K-like kinase protein, regulating checkpoint responses to DNA damage and replication stress. Apart from its checkpoint function in the nucleus, ATR actively engages in an antiapoptotic role at mitochondria following DNA damage.… read more here.
Keywords: trans atr; compartment specific; isomerization; atr ... See more keywords