Proline cis/trans Conformational Selection Controls 14–3–3 Binding
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DOI: 10.1021/jacs.4c13462
Abstract: Intrinsically disordered protein regions (IDRs) are structurally dynamic yet functional, often interacting with other proteins through short linear motifs (SLiMs). Proline residues in IDRs introduce conformational heterogeneity on a uniquely slow time scale arising from… read more here.
Keywords: trans conformational; proline cis; proline; cis trans ... See more keywords