Histone acetylation together with DNA demethylation empowers higher plasticity in adipocytes to differentiate into osteoblasts.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2019.144274
Abstract: Bone regeneration has been a challenge for both researchers and clinicians. In the field of tissue engineering, much effort has been made to identify cell sources including stem cells. The present study aimed to induce… read more here.
Keywords: histone acetylation; acetylation; trans differentiation; tsa ... See more keywords
Cycloxygenase-2 inhibition potentiates trans-differentiation of Wharton's jelly-mesenchymal stromal cells into endothelial cells: Transplantation enhances neovascularization-mediated wound repair.
Sign Up to like & getrecommendations! Published in 2019 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2019.01.004
Abstract: BACKGROUND Neo-vascularization, an indispensible phenomenon for tissue regeneration, facilitates repair and remodeling of wound tissues. This process is impaired in chronic wounds due to reduced number and recruitment of endothelial cells (ECs), thereby necessitating development… read more here.
Keywords: mesenchymal stromal; wharton jelly; stromal cells; wound ... See more keywords
Role of oxidative stress in induction of trans-differentiation of neutrophils in patients with rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2022 at "Free Radical Research"
DOI: 10.1080/10715762.2022.2089567
Abstract: Abstract Rheumatoid arthritis (RA) is an autoimmune disorder whose etiopathology involves an interplay between genetic and environmental factors, with oxidative stress being a key contributory factor. This study aimed to establish the impact, if any,… read more here.
Keywords: trans differentiation; differentiation neutrophils; oxidative stress; rheumatoid arthritis ... See more keywords
Resveratrol inhibits restenosis through suppressing proliferation, migration and trans-differentiation of vascular adventitia fibroblasts via activating SIRT1.
Sign Up to like & getrecommendations! Published in 2023 at "Current medicinal chemistry"
DOI: 10.2174/0929867330666230505161041
Abstract: AIM After the balloon angioplasty, vascular adventitia fibroblasts (VAFs), which proliferate, trans-differentiate to myofibroblasts and migrate to neointima, are crucial in restenosis. Resveratrol (RSV) has been reported to protect the cardiovascular by reducing restenosis and… read more here.
Keywords: proliferation migration; migration trans; proliferation; trans differentiation ... See more keywords
The role of chondrocyte-to-osteoblast trans-differentiation in fetal bone dysplasia of mice caused by prenatal exposure to dexamethasone
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1120041
Abstract: Maternal exposure to dexamethasone can cause developmental toxicity of long bones in offspring. However, the effect of dexamethasone on the trans-differentiation of growth plate chondrocytes into osteoblasts and its role in bone dysplasia of fetuses… read more here.
Keywords: trans differentiation; growth plate; mice; exposure ... See more keywords
Transcript Profiling Identifies Gene Cohorts Controlled by Each Signal Regulating Trans-Differentiation of Epidermal Cells of Vicia faba Cotyledons to a Transfer Cell Phenotype
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2017.02021
Abstract: Transfer cells (TCs) support high rates of membrane transport of nutrients conferred by a plasma membrane area amplified by lining a wall labyrinth comprised of an uniform wall layer (UWL) upon which intricate wall ingrowth… read more here.
Keywords: trans differentiation; wall; etc specific; gene ... See more keywords
Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation
Sign Up to like & getrecommendations! Published in 2020 at "eLife"
DOI: 10.7554/elife.53381
Abstract: A highly aggressive subset of pancreatic ductal adenocarcinomas undergo trans-differentiation into the squamous lineage during disease progression. Here, we investigated whether squamous trans-differentiation of human and mouse pancreatic cancer cells can influence the phenotype of… read more here.
Keywords: trans differentiation; cancer cells; cancer; squamous trans ... See more keywords