Cenicriviroc inhibits trans‐endothelial passage of monocytes and is associated with impaired E‐selectin expression
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.5a0817-328rrr
Abstract: Incidences of cardiovascular diseases (CVD) are high among virologically suppressed HIV‐infected individuals. Monocyte activation and trafficking are key mechanisms in the evolution of CVD. We studied the ability of cenicriviroc (CVC), a dual C‐C chemokine… read more here.
Keywords: hiv; migration; expression; cenicriviroc ... See more keywords
Antibody-activated trans-endothelial delivery of mesoporous organosilica nanomedicine augments tumor extravasation and anti-cancer immunotherapy
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DOI: 10.1016/j.bioactmat.2020.12.023
Abstract: Tumor vasculature constitutes a formidable hurdle for the efficient delivery of cancer nanomedicine into tumors. The leverage of passive pathway through inter-endothelial gaps in tumor blood vessels might account for limited extravasation of nanomedicine into… read more here.
Keywords: tumor; delivery; antibody; extravasation ... See more keywords
Abstract 1029: Metastatic cancer cells activate endothelial RhoA-ROCK pathway for trans-endothelial migration
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-1029
Abstract: Metastasis is the process through which tumor cells disseminate from the primary tumor and colonize in distant parts of the body. Two of the steps in the metastatic process are the trans-migration of cancer cells… read more here.
Keywords: endothelial rhoa; trans endothelial; cancer cells; rhoa ... See more keywords