A trans‐omics assessment of gene–gene interaction in early‐stage NSCLC
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13345
Abstract: Epigenome‐wide gene–gene (G × G) interactions associated with non‐small‐cell lung cancer (NSCLC) survival may provide insights into molecular mechanisms and therapeutic targets. Hence, we proposed a three‐step analytic strategy to identify significant and robust G × G interactions that… read more here.
Keywords: interaction; step; gene gene; trans omics ... See more keywords
2SBP: overview of the trans-omics session—measure × analyze metabolic adaptation of biological systems—at the 2019 BSJ Meeting in Miyazaki
Sign Up to like & getrecommendations! Published in 2020 at "Biophysical Reviews"
DOI: 10.1007/s12551-020-00660-1
Abstract: Elucidation of the molecular mechanism underlying the metabolic adaptation is critical to understand homeostasis of life. This review provides the concept, experimental and computational methods, to deal with this issue using “trans-omics” approaches. read more here.
Keywords: 2sbp overview; trans omics; metabolic adaptation; omics session ... See more keywords
Advancing stroke genomic research in the age of Trans-Omics big data science: Emerging priorities and opportunities
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2017.09.021
Abstract: BACKGROUND We systematically reviewed the genetic variants associated with stroke in genome-wide association studies (GWAS) and examined the emerging priorities and opportunities for rapidly advancing stroke research in the era of Trans-Omics science. METHODS Using… read more here.
Keywords: research; science; trans omics; advancing stroke ... See more keywords
TRANSDIRE: data-driven direct reprogramming by a pioneer factor-guided trans-omics approach
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac209
Abstract: MOTIVATION Direct reprogramming involves the direct conversion of fully differentiated mature cell types into various other cell types while bypassing an intermediate pluripotent state (e.g., induced pluripotent stem cells). Cell differentiation by direct reprogramming is… read more here.
Keywords: trans omics; cell types; pioneer; direct reprogramming ... See more keywords
Identification of MicroRNA Targets of Capsicum spp. Using MiRTrans—a Trans-Omics Approach
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2017.00495
Abstract: The microRNA (miRNA) can regulate the transcripts that are involved in eukaryotic cell proliferation, differentiation, and metabolism. Especially for plants, our understanding of miRNA targets, is still limited. Early attempts of prediction on sequence alignments… read more here.
Keywords: mirna; targets capsicum; mirna transcript; mirna targets ... See more keywords
Associations between prefrontal PI (16:0/20:4) lipid, TNC mRNA, and APOA1 protein in schizophrenia: A trans-omics analysis in post-mortem brain
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2023.1145437
Abstract: Background Though various mechanisms have been proposed for the pathophysiology of schizophrenia, the full extent of these mechanisms remains unclear, and little is known about the relationships among them. We carried out trans-omics analyses by… read more here.
Keywords: tnc; schizophrenia; post mortem; trans omics ... See more keywords