Metabolism of deltamethrin and cis- and trans-permethrin by rat and human liver microsomes, liver cytosol and plasma preparations
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DOI: 10.1080/00498254.2018.1451011
Abstract: Abstract The metabolism of deltamethrin (DLM), cis-permethrin (CPM) and trans-permethrin (TPM) was studied in liver microsomes, liver cytosol and plasma from male Sprague–Dawley rats aged 15, 21 and 90 days and from adult humans. DLM… read more here.
Keywords: tpm; metabolism deltamethrin; microsomes liver; ces enzymes ... See more keywords
Age Dependency of Blood-Brain Barrier Penetration by cis- and trans-Permethrin in the Rat
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DOI: 10.1124/dmd.118.084822
Abstract: Permethrin (PER), a type I pyrethroid, is the most widely used insecticide in domestic settings in the United States. The overall objective of this study was to assess the efficiency of the blood-brain barrier (BBB)… read more here.
Keywords: cis; blood brain; trans permethrin; brain barrier ... See more keywords
Plasma Protein and Lipoprotein Binding of Cis- and Trans-Permethrin and Deltamethrin in Adult Humans and Rats
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DOI: 10.1124/dmd.118.085464
Abstract: The majority of residents of the United States, Canada, and Europe are exposed to pyrethroids, the most commonly used class of insecticides. Surprisingly little is known about key aspects of their pharmacokinetics, including their mode… read more here.
Keywords: cis; protein; plasma; human plasma ... See more keywords