Articles with "trans retinoic" as a keyword



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The effect of all‐trans retinoic acid on the mitochondrial function and survival of cardiomyoblasts exposed to local photodamage

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Published in 2022 at "Cell Biology International"

DOI: 10.1002/cbin.11784

Abstract: Using H9C2 cardiomyoblasts, we have shown that all‐trans retinoic acid (ATRA), the biologically active metabolite of vitamin A, affects mitochondrial dynamics and functions. The low dose (10 nM) ATRA stimulates the expression of nuclear retinoid receptors… read more here.

Keywords: effect; survival; retinoic acid; cells treated ... See more keywords
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Influence of all‐trans retinoic acid on sperm metabolism and oxidative stress: Its involvement in the physiopathology of varicocele‐associated male infertility

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Published in 2018 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.26872

Abstract: The mechanisms by which varicocele affects fertility remain undetermined. Vitamin A (all‐trans retinoic acid [ATRA]) is required for fertility and normal spermatogenesis; however, the mechanisms driving its action are not defined yet. Previously, we demonstrated… read more here.

Keywords: trans retinoic; sperm metabolism; metabolism; retinoic acid ... See more keywords
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All-trans retinoic acid in combination with sodium butyrate enhances specific monoclonal antibody productivity in recombinant CHO cell line

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Published in 2018 at "Bioprocess and Biosystems Engineering"

DOI: 10.1007/s00449-018-1927-y

Abstract: The effects of all-trans retinoic acid (RA) and sodium butyrate (NaBu) on growth, viability and antibody production of two types of transfected Chinese hamster ovary cell lines (CHO-K1 and CHO-S) were investigated using a batch… read more here.

Keywords: trans retinoic; antibody; concentration; cho ... See more keywords
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All-trans retinoic acid enhances the effect of Fra-1 to inhibit cell proliferation and metabolism in cervical cancer

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Published in 2020 at "Biotechnology Letters"

DOI: 10.1007/s10529-020-02847-8

Abstract: Objectives This study on all-trans retinoic acid was designed to explore its effect on the ability of Fra-1 to cervical cancer cell development. The results show that all-trans retinoic acid enhances the effect of Fra-1… read more here.

Keywords: trans retinoic; cervical cancer; effect; retinoic acid ... See more keywords
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All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia–Reperfusion Injury in Rats by Inhibiting the Loss of the Blood–Brain Barrier via the JNK/P38MAPK Signaling Pathway

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Published in 2018 at "Neurochemical Research"

DOI: 10.1007/s11064-018-2545-4

Abstract: All-trans retinoic acid (ATRA) influences the outcomes of cerebral ischemic reperfusion (CIR) injury, but the mechanism remains unclear. The present study aimed to investigate the effects of ATRA on loss of the blood brain barrier… read more here.

Keywords: trans retinoic; cir; jnk; pathway ... See more keywords
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Cell dynamics during differentiation therapy with all-trans retinoic acid in acute promyelocytic leukemia

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Published in 2018 at "International Journal of Hematology"

DOI: 10.1007/s12185-018-2472-9

Abstract: The introduction of all-trans retinoic acid (ATRA) has made acute promyelocytic leukemia (APL) a curable disease; however, early death prior to the completion of treatment remains a problem. In quantitative evaluation of response to ATRA… read more here.

Keywords: trans retinoic; acute promyelocytic; promyelocytic leukemia; differentiation ... See more keywords
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Inhalable poly(lactic‐co‐glycolic acid) (PLGA) microparticles encapsulating all‐trans‐Retinoic acid (ATRA) as a host‐directed, adjunctive treatment for Mycobacterium tuberculosis infection

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Published in 2019 at "European Journal of Pharmaceutics and Biopharmaceutics"

DOI: 10.1016/j.ejpb.2018.10.020

Abstract: Graphical abstract Figure. No caption available. Abstract Ending the tuberculosis (TB) epidemic by 2030 was recently listed in the United Nations (UN) Sustainable Development Goals alongside HIV/AIDS and malaria as it continues to be a… read more here.

Keywords: trans retinoic; treatment; pathology; mycobacterium tuberculosis ... See more keywords
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A novel all‐trans retinoic acid derivative inhibits proliferation and induces apoptosis of myelodysplastic syndromes cell line SKM‐1 cells via up‐regulating p53

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Published in 2018 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2018.10.041

Abstract: &NA; Myelodysplastic syndromes (MDS) are a varied set of hematologic neoplasms and a high risk of progression to acute myeloid leukemia (AML). 4‐Amino‐2‐trifluoromethyl‐phenyl retinate (ATPR), a novel all‐trans retinoic acid (ATRA) derivative, play an important… read more here.

Keywords: trans retinoic; myelodysplastic syndromes; skm cells; novel trans ... See more keywords
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Supplementation comprising dietary fish oil with all-trans retinoic acid decreased blood lipids and fat accumulation in C57BL/6J mice

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Published in 2019 at "Journal of Functional Foods"

DOI: 10.1016/j.jff.2018.11.010

Abstract: Abstract This study aimed to assess the effects of fish oil plus all-trans retinoic acid (ATRA) on lipid metabolism and fat accumulation. Forty male C57BL/6J mice were divided into four groups; the FO, SO, FR,… read more here.

Keywords: fish oil; trans retinoic; fat accumulation; oil ... See more keywords
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Predictive role of vitamin A serum concentration in psoriatic patients treated with IL-17 inhibitors to prevent skin and systemic fungal infections.

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Published in 2020 at "Journal of pharmacological sciences"

DOI: 10.1016/j.jphs.2020.06.003

Abstract: The use of biological drugs in psoriasis is replacing traditional therapies due to their specific mechanism and limited side effects. However, the use of Interleukin 17 inhibitors and the modification of its cytokine pathway could… read more here.

Keywords: trans retinoic; patients treated; interleukin inhibitors; psoriatic patients ... See more keywords
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Rate of differentiation syndrome in patients based on timing of initial all-trans retinoic acid administration

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Published in 2019 at "Leukemia Research Reports"

DOI: 10.1016/j.lrr.2019.100189

Abstract: All-trans-retinoic acid (ATRA) is the standard of care for the management of acute promyelocytic leukemia (APL), but can be associated with differentiation syndrome (DS). Over a seven-year period, we sought to determine the impact of… read more here.

Keywords: retinoic acid; trans retinoic; differentiation syndrome; administration ... See more keywords