The effect of all‐trans retinoic acid on the mitochondrial function and survival of cardiomyoblasts exposed to local photodamage
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11784
Abstract: Using H9C2 cardiomyoblasts, we have shown that all‐trans retinoic acid (ATRA), the biologically active metabolite of vitamin A, affects mitochondrial dynamics and functions. The low dose (10 nM) ATRA stimulates the expression of nuclear retinoid receptors… read more here.
Keywords: effect; survival; retinoic acid; cells treated ... See more keywords
Long‐term follow‐up of a phase 2 study of all‐trans retinoic acid, arsenic trioxide, and gemtuzumab ozogamicin in acute promyelocytic leukemia
Sign Up to like & getrecommendations! Published in 2024 at "Cancer"
DOI: 10.1002/cncr.35662
Abstract: All‐trans retinoic acid (ATRA) and arsenic trioxide (ATO) combinations have produced excellent outcomes in patients with standard‐risk acute promyelocytic leukemia (APL). Herein, the authors update their long‐term results with the regimen of ATO‐ATRA and gemtuzumab… read more here.
Keywords: trans retinoic; retinoic acid; acute promyelocytic; long term ... See more keywords
Influence of all‐trans retinoic acid on sperm metabolism and oxidative stress: Its involvement in the physiopathology of varicocele‐associated male infertility
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26872
Abstract: The mechanisms by which varicocele affects fertility remain undetermined. Vitamin A (all‐trans retinoic acid [ATRA]) is required for fertility and normal spermatogenesis; however, the mechanisms driving its action are not defined yet. Previously, we demonstrated… read more here.
Keywords: trans retinoic; sperm metabolism; metabolism; retinoic acid ... See more keywords
All-trans retinoic acid in combination with sodium butyrate enhances specific monoclonal antibody productivity in recombinant CHO cell line
Sign Up to like & getrecommendations! Published in 2018 at "Bioprocess and Biosystems Engineering"
DOI: 10.1007/s00449-018-1927-y
Abstract: The effects of all-trans retinoic acid (RA) and sodium butyrate (NaBu) on growth, viability and antibody production of two types of transfected Chinese hamster ovary cell lines (CHO-K1 and CHO-S) were investigated using a batch… read more here.
Keywords: trans retinoic; antibody; concentration; cho ... See more keywords
All-trans retinoic acid enhances the effect of Fra-1 to inhibit cell proliferation and metabolism in cervical cancer
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Letters"
DOI: 10.1007/s10529-020-02847-8
Abstract: Objectives This study on all-trans retinoic acid was designed to explore its effect on the ability of Fra-1 to cervical cancer cell development. The results show that all-trans retinoic acid enhances the effect of Fra-1… read more here.
Keywords: trans retinoic; cervical cancer; effect; retinoic acid ... See more keywords
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia–Reperfusion Injury in Rats by Inhibiting the Loss of the Blood–Brain Barrier via the JNK/P38MAPK Signaling Pathway
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemical Research"
DOI: 10.1007/s11064-018-2545-4
Abstract: All-trans retinoic acid (ATRA) influences the outcomes of cerebral ischemic reperfusion (CIR) injury, but the mechanism remains unclear. The present study aimed to investigate the effects of ATRA on loss of the blood brain barrier… read more here.
Keywords: trans retinoic; cir; jnk; pathway ... See more keywords
All-Trans Retinoic Acid-Induced Cell Surface Heat Shock Protein 90 Mediates Tau Protein Internalization and Degradation in Human Microglia
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Neurobiology"
DOI: 10.1007/s12035-024-04295-1
Abstract: This study investigates the role of all-trans retinoic acid (ATRA) in modulating the expression of heat shock protein 90 (Hsp90) and its influence on the uptake and degradation of tau proteins in immortalized human microglia… read more here.
Keywords: trans retinoic; degradation; tau protein; internalization ... See more keywords
Cell dynamics during differentiation therapy with all-trans retinoic acid in acute promyelocytic leukemia
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Hematology"
DOI: 10.1007/s12185-018-2472-9
Abstract: The introduction of all-trans retinoic acid (ATRA) has made acute promyelocytic leukemia (APL) a curable disease; however, early death prior to the completion of treatment remains a problem. In quantitative evaluation of response to ATRA… read more here.
Keywords: trans retinoic; acute promyelocytic; promyelocytic leukemia; differentiation ... See more keywords
Inhalable poly(lactic‐co‐glycolic acid) (PLGA) microparticles encapsulating all‐trans‐Retinoic acid (ATRA) as a host‐directed, adjunctive treatment for Mycobacterium tuberculosis infection
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2018.10.020
Abstract: Graphical abstract Figure. No caption available. Abstract Ending the tuberculosis (TB) epidemic by 2030 was recently listed in the United Nations (UN) Sustainable Development Goals alongside HIV/AIDS and malaria as it continues to be a… read more here.
Keywords: trans retinoic; treatment; pathology; mycobacterium tuberculosis ... See more keywords
A novel all‐trans retinoic acid derivative inhibits proliferation and induces apoptosis of myelodysplastic syndromes cell line SKM‐1 cells via up‐regulating p53
Sign Up to like & getrecommendations! Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2018.10.041
Abstract: &NA; Myelodysplastic syndromes (MDS) are a varied set of hematologic neoplasms and a high risk of progression to acute myeloid leukemia (AML). 4‐Amino‐2‐trifluoromethyl‐phenyl retinate (ATPR), a novel all‐trans retinoic acid (ATRA) derivative, play an important… read more here.
Keywords: trans retinoic; myelodysplastic syndromes; skm cells; novel trans ... See more keywords
Supplementation comprising dietary fish oil with all-trans retinoic acid decreased blood lipids and fat accumulation in C57BL/6J mice
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2018.11.010
Abstract: Abstract This study aimed to assess the effects of fish oil plus all-trans retinoic acid (ATRA) on lipid metabolism and fat accumulation. Forty male C57BL/6J mice were divided into four groups; the FO, SO, FR,… read more here.
Keywords: fish oil; trans retinoic; fat accumulation; oil ... See more keywords