Palladium-Catalyzed Intermolecular Trans-Selective Carbofunctionalization of Internal Alkynes to Highly Functionalized Alkenes
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DOI: 10.1021/acscatal.0c02522
Abstract: A palladium/DPEphos-catalyzed intermolecular trans-selective carbofunctionalization of internal alkynes has been established herein. This method proceeds through a formal anti-carbopalladation, for... read more here.
Keywords: catalyzed intermolecular; internal alkynes; intermolecular trans; selective carbofunctionalization ... See more keywords
trans-Selective and Switchable Arene Hydrogenation of Phenol Derivatives
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DOI: 10.1021/acscatal.0c03423
Abstract: A trans-selective arene hydrogenation of abundant phenol derivatives catalyzed by a commercially available heterogeneous palladium catalyst is reported. The described method tolerates a variety of functional groups and provides access to a broad scope of… read more here.
Keywords: trans selective; phenol derivatives; selective switchable; hydrogenation ... See more keywords
Transition Metal-Free trans-Selective Alkynylboration of Alkynes.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b06212
Abstract: We report the first transition metal-free and trans-selective alkynylboration reaction of alkynes. This unprecedented carboboration reaction is enabled by pseudo-intramolecular activation of alkynylboronates using propargylic alcohols. The carboboration affords 4-alkynyl-1,2-oxaborol-2(5H)-ols, which are not only versatile… read more here.
Keywords: free trans; transition metal; trans selective; selective alkynylboration ... See more keywords
Iridium-catalyzed asymmetric trans-selective hydrogenation of 1,3-disubstituted isoquinolines
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DOI: 10.1039/d1sc06729j
Abstract: The development of the first asymmetric trans-selective hydrogenation of 1,3-disubstituted isoquinolines is reported. Utilizing [Ir(cod)Cl]2 and a commercially available chiral Josiphos ligand, a variety of differentially substituted isoquinolines are hydrogenated to produce enantioenriched trans-tetrahydroisoquinolines in… read more here.
Keywords: hydrogenation disubstituted; hydrogenation; disubstituted isoquinolines; asymmetric trans ... See more keywords
Trans-selective cyclizations of alpha-bromocarboxamides and E/Z-mixed internal olefins catalyzed by a Fe salt.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc04796a
Abstract: There are several reports of lactam cyclizations, but most yield less-substituted lactam rings. Therefore, diastereoselective cyclization to yield highly substituted lactams is one of the challenges in this field. We therefore propose a strategy involving… read more here.
Keywords: selective cyclizations; alpha bromocarboxamides; internal olefins; trans selective ... See more keywords