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Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz1204
Abstract: Abstract In order to discover new antibiotics with improved activity and selectivity, we created a reliable in vitro reporter system to detect trans-translation activity, the main mechanism for recycling ribosomes stalled on problematic messenger RNA…
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Keywords:
trans translation;
green fluorescent;
fluorescent protein;
protein vitro ... See more keywords
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Published in 2018 at "mBio"
DOI: 10.1128/mbio.02436-18
Abstract: Francisella tularensis is a highly infectious intracellular pathogen that kills more than half of infected humans if left untreated. F. tularensis has also been classified as a potential bioterrorism agent with a great risk for…
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Keywords:
trans translation;
rescue;
ribosome rescue;
activity ... See more keywords