trans-δ-Viniferin inhibits Ca2+-activated Cl- channels and improves diarrhea symptoms.
Sign Up to like & getrecommendations! Published in 2019 at "Fitoterapia"
DOI: 10.1016/j.fitote.2019.104367
Abstract: Ca2+-activated Cl- channels (CaCCs) wildly exist in many tissues which play an important role in ion transport and excitation conduction, especially fluid secretion and smooth muscle contraction in epithelial tissues. TMEM16A as a classic CaCC… read more here.
Keywords: tvn; ca2 activated; diarrhea; viniferin inhibits ... See more keywords
Trans-ε-viniferin as an inhibitor of TMEM16A preventing intestinal smooth muscle contraction.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Asian natural products research"
DOI: 10.1080/10286020.2023.2165067
Abstract: TMEM16A regulator is an important tool to study the physiological functions and pathogenesis related to TMEM16A. In the present study, trans-ε-viniferin (TV) was identified as a TMEM16A inhibitor with inhibitory activity against TMEM16A mediated Cl-… read more here.
Keywords: intestinal smooth; trans viniferin; muscle contraction; inhibitor ... See more keywords
The mechanism of trans-δ-viniferin inhibiting the proliferation of lung cancer cells A549 by targeting the mitochondria
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1190127
Abstract: Trans-δ-viniferin (TVN), as a natural extract, is a resveratrol dimer with attractive biological activities, particularly its anti-tumor character. However, the mechanism of TVN interfering with cancerous proliferation has not been fully understood. Herein in this… read more here.
Keywords: lung cancer; proliferation; trans viniferin; mechanism ... See more keywords