In vitro-transcribed antigen receptor mRNA nanocarriers for transient expression in circulating T cells in vivo
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DOI: 10.1038/s41467-020-19486-2
Abstract: Engineering chimeric antigen receptors (CAR) or T cell receptors (TCR) helps create disease-specific T cells for targeted therapy, but the cost and rigor associated with manufacturing engineered T cells ex vivo can be prohibitive, so… read more here.
Keywords: cells vivo; circulating cells; transcribed antigen; vitro transcribed ... See more keywords