Differential Activity of Transcribed Enhancers in the Prefrontal Cortex of 537 cases with Schizophrenia and Controls
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DOI: 10.1038/s41380-018-0059-8
Abstract: Transcription at enhancers is a widespread phenomenon which produces so-called enhancer RNA (eRNA) and occurs in an activity-dependent manner. However, the role of eRNA and its utility in exploring disease-associated changes in enhancer function, and… read more here.
Keywords: transcribed enhancers; schizophrenia; activity transcribed; expression ... See more keywords
Sequence Characteristics Distinguish Transcribed Enhancers from Promoters and Predict Their Breadth of Activity
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DOI: 10.1534/genetics.118.301895
Abstract: Enhancers and promoters both regulate gene expression by recruiting transcription factors (TFs); however, the degree to which enhancer vs. promoter activity is due to differences in their sequences or to genomic context is the subject… read more here.
Keywords: transcribed enhancers; activity; enhancers promoters; promoter ... See more keywords
Genome-wide Identification and Characterization of Enhancers Across 10 Human Tissues
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DOI: 10.7150/ijbs.26605
Abstract: Background: Enhancers can act as cis-regulatory elements (CREs) to control development and cellular function by regulating gene expression in a tissue-specific and ubiquitous manner. However, the regulatory network and characteristic of different types of enhancers… read more here.
Keywords: transcribed enhancers; tissue specific; enhancers enh; enhancers across ... See more keywords