A survey of the complex transcriptome from the highly polyploid sugarcane genome using full-length isoform sequencing and de novo assembly from short read sequencing
Sign Up to like & getrecommendations! Published in 2017 at "BMC Genomics"
DOI: 10.1186/s12864-017-3757-8
Abstract: BackgroundDespite the economic importance of sugarcane in sugar and bioenergy production, there is not yet a reference genome available. Most of the sugarcane transcriptomic studies have been based on Saccharum officinarum gene indices (SoGI), expressed… read more here.
Keywords: length; full length; sugarcane; genome ... See more keywords
CRISPRi enables isoform-specific loss-of-function screens and identification of gastric cancer-specific isoform dependencies
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DOI: 10.1186/s13059-021-02266-6
Abstract: Introduction Genes contain multiple promoters that can drive the expression of various transcript isoforms. Although transcript isoforms from the same gene could have diverse and non-overlapping functions, current loss-of-function methodologies are not able to differentiate… read more here.
Keywords: loss function; isoform specific; transcript isoforms;
Genetic Control of Splicing at SIRPG Modulates Risk of Type 1 Diabetes.
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DOI: 10.2337/db21-0194
Abstract: Signal regulatory protein SIRPĪ³ (CD172G) is expressed on the surface of lymphocytes where it acts by engaging its ligand, CD47. SIRPG, which encodes SIRPĪ³, contains a non-synonymous coding variant, rs6043409, which is significantly associated with… read more here.
Keywords: risk type; transcript isoforms; type diabetes; sirpg ... See more keywords