Expression Analysis of BDNF, BACE1, and Their Natural Occurring Antisenses in Autistic Patients
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-019-01432-7
Abstract: Autism spectrum disorder (ASD) as a multifaceted neurological syndrome affects many aspects of neuropsychologic functions. Dysregulated expressions of several genes have been documented in ASD patients. The current project aimed at comparison of transcript levels… read more here.
Keywords: age; transcript levels; natural occurring; bace1 natural ... See more keywords
The cre-inducer doxycycline lowers cytokine and chemokine transcript levels in the gut of mice
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Applied Genetics"
DOI: 10.1007/s13353-017-0401-x
Abstract: The antibiotic doxycycline is used as an inducer of recombinase (cre)-based conditional gene knockout in mice, which is a common tool to show the effect of disrupted gene functions only in one period of a… read more here.
Keywords: inducer doxycycline; cre inducer; transcript levels; gene ... See more keywords
Lycopene cyclases determine high α-/β-carotene ratio and increased carotenoids in bananas ripening at high temperatures.
Sign Up to like & getrecommendations! Published in 2019 at "Food chemistry"
DOI: 10.1016/j.foodchem.2018.12.121
Abstract: Bananas are a recommended food source to alleviate vitamin A deficiency because they contain a high ratio of provitamin A precursors. The objective of this study was to investigate carotenoid accumulation pattern in banana fruits… read more here.
Keywords: high carotene; carotene ratio; carotene; ratio ... See more keywords
Analysis of transcript levels of a few schizophrenia candidate genes in neurons from a transgenic mouse embryonic stem cell model overexpressing DNA Methyltransferase 1 (DNMT1).
Sign Up to like & getrecommendations! Published in 2020 at "Gene"
DOI: 10.1016/j.gene.2020.144934
Abstract: Overexpression of DNA Methyltransferase I (DNMT1) is considered as one of the etiological factors for schizophrenia (SZ). However, information on genes subjected to dysregulation because of DNMT1 overexpression is limited. To test whether a larger… read more here.
Keywords: tet tet; dysregulation; transcript levels; dnmt1 ... See more keywords
DNMT3A mutant transcript levels persist in remission and do not predict outcome in patients with acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2018 at "Leukemia"
DOI: 10.1038/leu.2017.200
Abstract: We investigated the prognostic impact of minimal residual disease (MRD) monitoring in acute myeloid leukemia patients harboring DNA methyltransferase 3A-R882H/-R882C mutations (DNMT3Amut). MRD was determined by real-time quantitative PCR (RQ-PCR) in 1494 samples of 181… read more here.
Keywords: remission; dnmt3amut transcript; transcript levels; transcript ... See more keywords
P–533 Effects of sex chromosomal complement, XX, XO, or XY, on the transcriptome and development of mouse oocytes during follicular growth
Sign Up to like & getrecommendations! Published in 2021 at "Human Reproduction"
DOI: 10.1093/humrep/deab130.532
Abstract: How does the sex chromosome complement affect the transcriptome and development of oocytes during follicular growth in the mouse ovary? Highly expressed X-linked genes adjust their transcript levels according to the X dosage. Y-linked genes… read more here.
Keywords: follicular growth; complement; transcript levels; growth ... See more keywords
Alu insertion variants alter gene transcript levels.
Sign Up to like & getrecommendations! Published in 2021 at "Genome research"
DOI: 10.1101/gr.261305.120
Abstract: Alu are high copy number interspersed repeats that have accumulated near genes during primate and human evolution. They are a pervasive source of structural variation in modern humans. Impacts that Alu insertions may have on… read more here.
Keywords: insertion; transcript levels; insertion variants; gene ... See more keywords
Transcript levels of plastin 3 and neuritin 1 modifier genes in spinal muscular atrophy siblings
Sign Up to like & getrecommendations! Published in 2017 at "Pediatrics International"
DOI: 10.1111/ped.13052
Abstract: In single gene disorders, patients with the same genotype may have variations in severity. One of the main factors affecting disease severity is modifier genes. Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder… read more here.
Keywords: spinal muscular; modifier genes; genes spinal; transcript levels ... See more keywords
Tumor MK2 transcript levels are associated with improved response to chemotherapy and patient survival in NSCLC.
Sign Up to like & getrecommendations! Published in 2023 at "Physiological genomics"
DOI: 10.1152/physiolgenomics.00155.2022
Abstract: RATIONALE Non-small cell lung cancers (NSCLC) demonstrate intrinsic resistance to cell death, even after chemotherapy. Previous work suggested defective nuclear translocation of active caspase-3 in observed resistance to cell death. We have identified mitogen activated… read more here.
Keywords: tumor; survival; mk2 transcript; transcript levels ... See more keywords
High FA2H and UGT8 transcript levels predict hydroxylated hexosylceramide accumulation in lung adenocarcinoma[S]
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Lipid Research"
DOI: 10.1194/jlr.m093955
Abstract: Lung cancer causes more deaths than any other cancer. Sphingolipids encompass metabolically interconnected species whose balance has pivotal effects on proliferation, migration, and apoptosis. In this study, we paralleled quantification of sphingolipid species with quantitative… read more here.
Keywords: lung; ugt8 transcript; transcript levels; cancer ... See more keywords
MON-118 Biochemical and Clinical Correlates of Subcutaneous Adipose mRNA Transcript Levels in Men with T2DM
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Endocrine Society"
DOI: 10.1210/js.2019-mon-118
Abstract: Abstract Background: Altered profiles of subcutaneous adipose tissue gene expression have been independently associated with insulin sensitivity. T2DM has been associated with higher levels of adipokines, inflammatory cytokines and lower plasma sex steroid concentrations. We… read more here.
Keywords: expression; independently associated; transcript levels; subcutaneous adipose ... See more keywords