Articles with "transcriptase htert" as a keyword



A phase 1 trial of human telomerase reverse transcriptase (hTERT) vaccination combined with therapeutic strategies to control immune-suppressor mechanisms

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Published in 2024 at "Experimental Biology and Medicine"

DOI: 10.3389/ebm.2024.10021

Abstract: The presence of inhibitory immune cells and difficulty in generating activated effector T cells remain obstacles to development of effective cancer vaccines. We designed a vaccine regimen combining human telomerase reverse transcriptase (hTERT) peptides with… read more here.

Keywords: phase trial; telomerase reverse; transcriptase htert; vaccination ... See more keywords