Elevated levels of the methyltransferase SETD2 causes transcription and alternative splicing changes resulting in oncogenic phenotypes
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DOI: 10.3389/fcell.2022.945668
Abstract: The methyltransferase SETD2 regulates cryptic transcription, alternative splicing, and the DNA damage response. It is mutated in a variety of cancers and is believed to be a tumor suppressor. Counterintuitively, despite its important role, SETD2… read more here.
Keywords: transcription alternative; alternative splicing; methyltransferase setd2;