Methyltransferase Detection Based on Target-Responsive Transcription Amplification of Light-Up Aptamer.
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DOI: 10.1021/acs.analchem.5c05886
Abstract: The sensitive and accurate evaluation of DNA methyltransferases (MTases) is essential for biomedical and synthetic biology applications. However, existing approaches have limited applications because they are labor-intensive with low sensitivity, require sophisticated instruments, and involve… read more here.
Keywords: detection; light aptamer; transcription amplification; mtase ... See more keywords
Cascade Transcription Amplification of RNA Aptamer for Ultrasensitive MicroRNA Detection.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b00124
Abstract: MicroRNAs (miRNAs) play a critical role in multifarious biological processes and being deemed to be important biomarkers for clinical cancer diagnosis, prognosis, and therapy. Thus, assays for sensitive and accurate quantification of miRNAs are highly… read more here.
Keywords: detection; cascade transcription; rna aptamer; transcription amplification ... See more keywords