Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl.
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DOI: 10.1038/nature22063
Abstract: Mammalian genomes are spatially organized by CCCTC-binding factor (CTCF) and cohesin into chromatin loops and topologically associated domains, which have important roles in gene regulation and recombination. By binding to specific sequences, CTCF defines contact… read more here.
Keywords: mammalian genomes; cohesin; transcription ctcf; ctcf ... See more keywords