Direct visualization of cardiac transcription factories reveals regulatory principles of nuclear architecture during pathological remodeling.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2019.02.003
Abstract: Heart failure is associated with hypertrophying of cardiomyocytes and changes in transcriptional activity. Studies from rapidly dividing cells in culture have suggested that transcription may be compartmentalized into factories within the nucleus, but this phenomenon… read more here.
Keywords: transcription; rna polymerase; nuclear architecture; transcription factories ... See more keywords
Wheat Breeding, Transcription Factories, and Genetic Interactions: New Perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.807884
Abstract: Epistatic interactions and negative heterosis have been shown to be associated with interchromosomal interactions in wheat. Physical gene-gene interactions between co-regulated genes clustered in “transcription factories” have been documented, and a genome-wide atlas of functionally… read more here.
Keywords: new perspectives; perspectives wheat; wheat breeding; transcription factories ... See more keywords
G-Quadruplex Structures Colocalize with Transcription Factories and Nuclear Speckles Surrounded by Acetylated and Dimethylated Histones H3
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22041995
Abstract: G-quadruplexes (G4s) are four-stranded helical structures that regulate several nuclear processes, including gene expression and telomere maintenance. We observed that G4s are located in GC-rich (euchromatin) regions and outside the fibrillarin-positive compartment of nucleoli. Genomic… read more here.
Keywords: nuclear speckles; quadruplex structures; structures colocalize; transcription factories ... See more keywords