Methylation and transcription patterns are distinct in IDH mutant gliomas compared to other IDH mutant cancers
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-45346-1
Abstract: Mutations in isocitrate dehydrogenases 1 and 2 (IDHmut) are present in a variety of cancers, including glioma, acute myeloid leukemia (AML), melanoma, and cholangiocarcinoma. These mutations promote hypermethylation, yet it is only a favorable prognostic… read more here.
Keywords: gliomas; gliomas compared; idh mutant; transcription patterns ... See more keywords
SETD2 regulates gene transcription patterns and is associated with radiosensitivity in lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.935601
Abstract: Lung adenocarcinoma (LUAD) has high morbidity and mortality worldwide, and its prognosis remains unsatisfactory. Identification of epigenetic biomarkers associated with radiosensitivity is beneficial for precision medicine in LUAD patients. SETD2 is important in repairing DNA… read more here.
Keywords: associated radiosensitivity; lung adenocarcinoma; transcription; transcription patterns ... See more keywords