Articles with "transcription profiles" as a keyword



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Microglial transcription profiles in mouse and human are driven by APOE4 and sex

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Published in 2021 at "iScience"

DOI: 10.1016/j.isci.2021.103238

Abstract: Summary Apolipoprotein E4 (APOE4) is the strongest genetic risk factor for sporadic Alzheimer’s disease (AD). APOE4 is known to affect the function of microglia, but to what extent this gene drives microglial gene expression has… read more here.

Keywords: transcription profiles; profiles mouse; mouse human; sex ... See more keywords