LAUSR

Transcription regulation through nascent RNA folding.

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1 Published in 2021 at "Journal of molecular biology"

DOI: 10.1016/j.jmb.2021.166975

Abstract: Folding of RNA into secondary structures through intramolecular base pairing determines an RNA's three-dimensional architecture and associated function. Simple RNA structures like stem loops can provide specialized functions independent of coding capacity, such as protein… read more here.

Keywords: transcription; rna; regulation nascent; nascent rna ... See more keywords

Dinucleosome specificity and allosteric switch of the ISW1a ATP-dependent chromatin remodeler in transcription regulation

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0 Published in 2020 at "Nature Communications"

DOI: 10.1038/s41467-020-19700-1

Abstract: Over the last 3 decades ATP-dependent chromatin remodelers have been thought to recognize chromatin at the level of single nucleosomes rather than higher-order organization of more than one nucleosome. We show the yeast ISW1a remodeler… read more here.

Keywords: chromatin; dinucleosome specificity; atp dependent; transcription regulation ... See more keywords

GTRD: a database on gene transcription regulation—2019 update

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1 Published in 2019 at "Nucleic Acids Research"

DOI: 10.1093/nar/gky1128

Abstract: Abstract The current version of the Gene Transcription Regulation Database (GTRD; http://gtrd.biouml.org) contains information about: (i) transcription factor binding sites (TFBSs) and transcription coactivators identified by ChIP-seq experiments for Homo sapiens, Mus musculus, Rattus norvegicus,… read more here.

Keywords: chip seq; transcription; gene transcription; gtrd ... See more keywords

Zebrafish optineurin: genomic organization and transcription regulation.

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1 Published in 2022 at "Genome"

DOI: 10.1139/gen-2022-0019

Abstract: Optineurin (OPTN) is involved in a variety of mechanisms such as autophagy, vesicle trafficking, and NF-κB signaling. Mutations in the OPTN gene have been associated with different pathologies including glaucoma, amyotrophic lateral sclerosis and Paget's… read more here.

Keywords: transcription regulation; optn; optn gene; regulation ... See more keywords

Algebraic Morphology of DNA-RNA Transcription and Regulation

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1 Published in 2023 at "Symmetry"

DOI: 10.3390/sym15030770

Abstract: Transcription factors (TFs) and microRNAs (miRNAs) are co-actors in genome-scale decoding and regulatory networks, often targeting common genes. To discover the symmetries and invariants of the transcription and regulation at the scale of the genome,… read more here.

Keywords: transcription regulation; dna; transcription; group ... See more keywords